genetics lecture 6

Question 1

Autosomal dominant disorders in humans

Answer 1

The normal allele is recessive and the abnormal (disease) allele is dominant

Question 2

what is the Pedigree pattern for dominant inheritance

Answer 2

Phenotype appears in every generation

Affected parents transmit the phenotype to both sons and daughters

Affected parents can produce unaffected off-spring

Question 3

what is meant by allele frequency

Answer 3

the proportion of a particular allele (variant of a gene) within a population

Question 4

what does Homozygous mean

Answer 4

both alleles the same e.g. AA

Question 5

Heterozygous

Answer 5

alleles different e.g. Aa

Question 6

homo and hetero

Answer 6

N.B. the dominant allele is usually depicted by a capital letter, therefore homozygous dominant = AA and homozygous recessive = aa

Question 7

Genotype

Answer 7

the inherited alleles of an individual

Question 8

Phenotype

Answer 8

the physical characteristics of an individual