genetics lecture 5

Question 1

Autosomal recessive trait

Answer 1

individual must inherit two copies of the recessive allele
, one from each parent.
Individuals with only one recessive allele are carriers; they do not show symptoms but can pass on the disease allele to their offspring.

Question 2

what is a autosomal recessive disorders

Answer 2

genetic conditions caused by mutations in genes located on autosomal chromosomes, which are chromosomes other than the sex chromosomes (X and Y).

Question 3

what causes albinism

Answer 3

mutation in one of several genes.

Question 4

what caues sickle cell anaemia

Answer 4

Caused by an abnormal type of haemoglobin called haemoglobin S

Question 5

what are the effects of sickle cell anemia

Answer 5

Haemoglobin S changes the shape of red blood cells, especially when the cells are exposed to low oxygen levels. The red blood cells become shaped like crescents or sickles.

Question 6

what is the dna base that changes in SCA

Answer 6

a valine is replaced by a glutamate in the protein (e.g. Mis-sense mutation).

Question 7

what are some results due to phentoypic expression

Answer 7

Anaemia
Fatigue
Shortness of breath