Genetics Exam Flashcards
Mendel’s Law of Independent Assortment
Inheritance of one trait is not dependent on inheritance of another because their genes are sorted separately
Mendel’s Law of Segregation
Requires that offspring can inherit only one version of an allele of a gene, no 2 homologous chromosomes can be inherited
Amino acids are created by how many nucleotides?
3
DNA nucleotide pairs
A and T
G and C
RNA nucleotide
A and U
G and C
Semi Conservative Replication
A single strand of DNA is used as a template for its respective partner
How many nucleotides are in a codon?
3
DNA Backbone
phosphate and a sugar which nucleotide extends from
What phase does DNA replication occur?
S phase
What phase are corrections made to DNA in?
G2 phase
Helicase
unwinds the DNA
Single strand binding proteins
hold DNA open during replication process
Primase
initiates DNA replication by synthesizing RNA primers
RNA Primers
RNA that initiates DNA synthesis
DNA Polymerase
adds nucleotides to the DNA strand being built
Direction of Replication
DNA polymerase can only build strands in the direction of 5’-3’ and the corresponding strand would be 3’-5’ in the direction of replication
Ligase
bind two strands of DNA together after replication to created a fully formed double helix
Okazaki Fragments
fragments of DNA synthesized on the lagging strand of DNA and fused together by the ligase
Germline Mutation
Occurs in the early cells before sperm and eggs are formed and can be passed onto the next generation
Soma Mutation
Occurs in the cells that aren’t incorporated in gamete production and are not passed onto the next generation
Polymerase Chain Reaction (PRC)
lab technique that produces millions of copies of DNA
Denaturation
first step of PCR, DNA is heated to separate the two complimentary strands
Annealing
second step of PCR, temperature is lowered so that DNA primers attach to regions around the segment of DNA to be copied
Elongation
third step of PCR, DNA polymerase copies the template segment of DNA