Genetics Exam Flashcards

1
Q

Mendel’s Law of Independent Assortment

A

Inheritance of one trait is not dependent on inheritance of another because their genes are sorted separately

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2
Q

Mendel’s Law of Segregation

A

Requires that offspring can inherit only one version of an allele of a gene, no 2 homologous chromosomes can be inherited

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3
Q

Amino acids are created by how many nucleotides?

A

3

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4
Q

DNA nucleotide pairs

A

A and T
G and C

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5
Q

RNA nucleotide

A

A and U
G and C

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6
Q

Semi Conservative Replication

A

A single strand of DNA is used as a template for its respective partner

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7
Q

How many nucleotides are in a codon?

A

3

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8
Q

DNA Backbone

A

phosphate and a sugar which nucleotide extends from

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9
Q

What phase does DNA replication occur?

A

S phase

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10
Q

What phase are corrections made to DNA in?

A

G2 phase

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11
Q

Helicase

A

unwinds the DNA

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12
Q

Single strand binding proteins

A

hold DNA open during replication process

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13
Q

Primase

A

initiates DNA replication by synthesizing RNA primers

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14
Q

RNA Primers

A

RNA that initiates DNA synthesis

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15
Q

DNA Polymerase

A

adds nucleotides to the DNA strand being built

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16
Q

Direction of Replication

A

DNA polymerase can only build strands in the direction of 5’-3’ and the corresponding strand would be 3’-5’ in the direction of replication

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17
Q

Ligase

A

bind two strands of DNA together after replication to created a fully formed double helix

18
Q

Okazaki Fragments

A

fragments of DNA synthesized on the lagging strand of DNA and fused together by the ligase

19
Q

Germline Mutation

A

Occurs in the early cells before sperm and eggs are formed and can be passed onto the next generation

20
Q

Soma Mutation

A

Occurs in the cells that aren’t incorporated in gamete production and are not passed onto the next generation

21
Q

Polymerase Chain Reaction (PRC)

A

lab technique that produces millions of copies of DNA

22
Q

Denaturation

A

first step of PCR, DNA is heated to separate the two complimentary strands

23
Q

Annealing

A

second step of PCR, temperature is lowered so that DNA primers attach to regions around the segment of DNA to be copied

24
Q

Elongation

A

third step of PCR, DNA polymerase copies the template segment of DNA

25
Last step of PCR
full process is repeated to obtain the desired amount of DNA
26
The Central Dogma of Molecular Biology
DNA is transcribed into messenger RNA and mRNA in translated into proteins, meaning DNA codes for protein synthesis
27
Transcription
synthesis of RNA from DNA
28
Translation
synthesis of proteins from RNA
29
Transcription process
DNA is separated and one strand is used as a template strand to make mRNA which is complementary to the template strand
30
RNA Polymerase
attaches to the template strand and synthesizes RNA molecule
31
Nucleosomes
DNA wraps around nucleosomes that attach, condensing the DNA into chromatids
32
Transcription Factors
bind to the DNA after separation to signal the RNA polymerase to begin
33
Terminator Sequence
A sequence of DNA that signals for the RNA polymerase to finish
34
rRNA
codes for the ribosome that creates proteins
35
tRNA
has an attach site for specific amino acids and anticodons that correspond to the mRNA codons
36
Ribosomes composed of
two subunits of rRNA and some proteins
37
Three steps of translation
initiation, elongation, and termination
38
Initiation
mRNA binds to a small ribosomal unit at the initiation codon and the larger ribosomal unit attaches making the initiation complex complete
39
Elongation
RNA codons are read and the polypeptides are formed and bonded
40
Termination
when the ribosome reaches the stop codon and detached, completing the translation
41
Ultraviolet radiation damages DNA by causing an extra ___________________ bond to form between adjacent ______________.
covalent, thymines.