genetics and inheritance Flashcards

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1
Q

genotype

A

all the genetic makeup of the organism

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2
Q

genepool

A

ll the alleles within an interbreeding population

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3
Q

population

A

all the individuals of the same species that occupy the same area

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4
Q

phenotype

A

expression of its genetic constitution and its interaction with the environment

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5
Q

alleles

A

different versions of the same gene

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6
Q

locus

A

position of allele on the homologous chromosomes

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7
Q

homozygous

A

two copies of a gene

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8
Q

heterozygous

A

two copies of gene are different alleles

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9
Q

co-dominant alleles

A

equally expressed in the phenotype

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10
Q

gene pool definition

A

all of the alleles of all the genes of all the individuals in a population at a given time

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11
Q

allelic frequency

A

The number of times an allele occurs within a gene pool

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12
Q

Hardy-Weinberg principle predicts that:

A

the allelic frequencies from one generation to the next will remain constant

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13
Q

factors affecting the Hardy-Weinberg principle

A

-no migration
-no gene mutation
-no selection for a particular allele

-large population
-random mating

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14
Q

Hardy-Weinberg equations

A

P + q = 1.0

P2 + 2Pq + q2 = 1.0

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15
Q

monohybrid inheritance meaning

A

inheritance of a single gene which determines a single characteristic

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16
Q

monohybrid inheritance -Codominance

A

do not show a standard dominant/recessive relationship
superscript letters are used for the allele

17
Q

monohybrid inheritance - multiple alleles

A

several genes in a population
dominance hierarchy

18
Q

There was 850 fruit flies in a population.
510 fruit flies had the genotype W(H)W(N)
255 fruit flies had the genotype W(N)W(V)
85 fruit flies had the genotype W(V)W(V)
CALCULATE ALLELE FREQUENCY OF ALLELE W(V)

A

1700 alleles in frequency
2x85=170
1x255=255
255+170=425
424/1700
0.25

19
Q

950 flies in population
frequency of W(V) allele. was 0.2
calculate the number of expected individuals with the genotype W(N)W(V)

A

2X0.2X0.8=0.32
0.32X950=
304

20
Q

dominant characteristics rules

A
  1. affected offspring must have at least one affected parent
  2. unaffected parents only have unaffected offspring
  3. if both parents are affected but child is unaffected, both parents must be heterozygous
21
Q

recessive characteristics

A

unaffected parents can have an affected offspring

22
Q

sex linked characteristics

A

controlled by genes located on one of sex chromosomes

23
Q

what are the male chromosomes

A

XY

24
Q

what are the female characteristics

A

XX

25
Q

why do men have more genetic diseases

A

For sex-linked genes, a female would have to have two copies of a recessive allele for it to appear in the phenotype, whereas males only need one.

26
Q

sex-link rules for recessive allele

A

-dads and daughters
daughter is affected
father is not affected
is recessive disease
so not sex-linked

27
Q

Dihybrid inheritance definition

A

a phenotype is inherited as a result of two different genes, thus two characteristics

28
Q

what is the ratio of dihybrid inheritence between homozygous parents?

A

9:3:3:1

29
Q

Autosomal linkage

A

chromosomes that are not directly involved in determining the sex of an organism.

30
Q

Crossing over process

A

Non sister chromatids on homologous pairs cross over to form a bivalent
Then forms a chiasma
Exchange of alleles to produce random recombinant offspring which display new combination of alleles

31
Q

Linkage group definition

A

Set of genes on the same chromosomes which tend to be inherited together

32
Q

What happens to the expected ratio when two genes are autosomal linked

A

Does not follow the expected phenotypic ratio

33
Q

What happens when genes are autosomal linked

A

Don’t follow the expected phenotypic ratio

34
Q

sex-linkage males vs females

A

female needs two copies of a recessive allele for it to appear in the phenotype, whereas males only need one

35
Q

sex link rules - how to look if it is not sex-linked

A

-if daughter is affected, father is not (recessive)
-if son is affected, mother is not affected (domindant)

36
Q

epistasis definition

A

interaction between two genes where one allele influences the expression of another