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Psychiatry > Genetics > Flashcards

Genetics Flashcards

1
Q

What is the heritability of HD?

A

AD

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2
Q

What gene causes HD?

A

Huntington gene- codes for huntington protein. Causes an expansion of the CAG triplet- codes for glutamine, so more repeats causes a longer chain of glutamines, which causes the huntington protein to be misshapen.

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3
Q

What characteristic does HD display related to inheritance?

A

Anticipation- earlier onset in each generation

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4
Q

What is executive function?

A

Planning
Abstract thinking
Cognitive flexibility

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5
Q

What are the characteristics of familial forms of Alzheimer’s?

A

More relatives affected
Relatives affected at a younger age
Unusual or atypical features

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6
Q

How genetic is bipolar disorder?

A

Very-unknown heritability
Dizygotic twins: 14%
Monozygotic: 57%

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7
Q

What evidence related to treatment of bipolar disorder is present regarding family members?

A

If one family member responds to a treatment, others will benefit from the same one

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Psychiatry (29 decks)

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