Genetics

Question 1

what did gottessman find

Answer 1

If a grandparent has schizophrenia there is a 5% chance of development whereas if a parent has it there is a 13% chance of development

BUT- retrospective data

Question 2

what did gottessman and shields find

Answer 2

42% concordance for mz twins and just 9% for dz twins

ELAB- over 26 years so allows for changes in diagnostic criteria

Question 3

what did tirarni find

Answer 3

5.4% of schizophrenics had mothers with the disorder compared to the 1% basline

Question 4

what is the percentage chance if living with the schizophrenic mother

Answer 4

13%

Question 5

What is an alternative explanation

Answer 5

predisposition of genes create a vulnerability

Question 6

what is a practical application

Answer 6

adoption to reduce the chances of onset

Question 7

what is the genetic explanation

Answer 7

the idea that schizophrenia runs in families and a specific gene is inherited

Question 8

why are family studies used

Answer 8

to define a relationship between the degree of closeness in a blood relative and the risk of developing schizophrenia by using medical data

Question 9

why are twin studies used

Answer 9

to find concordance rates of MZ and DZ twins to define whether the amount of shared genetics correlates with the likelihood of developing schizophrenia

Question 10

why are adoption studies used

Answer 10

to test genetics and the environment as one twin is adopted and one stays with the biological mother so the environment can be tested