Genetics Flashcards

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1
Q

Phenotype

A

The observable characteristics of an individual, usually resulting from the interaction between the organisms genotype and the environment in which it develops

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2
Q

Monogenic

A

Phenotype controlled by 1 gene

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3
Q

Polygenic

A

Phenotype controlled by many genes

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4
Q

Gene

A

A triplet sequence of nucleotide bases, found on the DNA strand, that codes for the production of a polypeptide.

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5
Q

Allele

A

One of a number of alternating forms of the same gene, responsible for determining varying characteristics. The nucleotide sequence of the gene varies to give different alleles.

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6
Q

Locus

A

Position of an allele on the DNA molecule aka the chromosome

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7
Q

Homozygous

A

The diploid condition in which the alleles at a given locus are identical

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8
Q

Heterozygous

A

The diploid condition in which the alleles at a given locus are different

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9
Q

Dominant

A

The allele which influences the appearance of the phenotype even in the presence of an alternative allele

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10
Q

Recessive

A

The allele which influences the appearance of the phenotype only in the presence of another recessive allele

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11
Q

F1 generation

A

The generation produced by crossing HOMOZYGOUS parental stocks (for e.g WW x ww)

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12
Q

F2 generation

A

The generation produced by crossing two F1 organisms ( Ww x Ww)

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13
Q

Genotype

A

The genetic constitution of an organism with respect to the alleles under consideration

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14
Q

Law of Segregation

A

A pair of alleles separates during gamete formation, as only one allele can be carried by each gamete. So, the members of an allele pair are found in two different gametes - one in the maternal and the other in the paternal. This segregation of alleles occurs during anaphase 1 of meiosis, when the bivalents separate

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15
Q

Law of independent assortment

A

Based upon evidence from the dihybrid cross, Mendel concluded that the presence of one type of allele (allele A/a)in a gamete does not affect which type of allele will be present for another trait (Allele B/b). The two genes segregate independently of each other during meiosis.

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16
Q

1:2:1

A

F2 generation from a monohybrid cross with codominance.

17
Q

1:1

A

Offspring from a monohybrid test cross with the unknown being heterozygous

18
Q

1:1:1:1

A

Offspring for a dihybrid cross with the unknown being heterozygous for both alleles.
&
F2 from sex-linked cross in which the female was homozygous recessive and the male was dominant.

19
Q

Epistasis

A

When the effect of one gene is dependent on the presence of one or more modifier genes.

Dominant = 12:3:1- any dominant form of epistatic allele masks
Recessive = 9:4:3 - recessive homozygous form of epistatic allele masks

If it doesn’t mask, the other genes determine the phenotype

20
Q

Insulin

A

The Gene used in insulin production is obtained by reverse transcription in pancreatic beta (B) cells or restriction enzymes