genetics Flashcards
1
Q
how many genes do we have
A
21-25000
2
Q
how much of our DNA is made up of genes
A
1-2%
3
Q
what is the promotor region for translation
A
TATA box - 5’
4
Q
which direction is DNA replication
A
5’–>3’
Okazaki fragments in lagging strand
5
Q
what happens to the similarity of our genome with each degree of relationship
A
each degree of relationship = halves the genes
6
Q
when do you often seen autosomal recessive diseases
A
mating of related individuals = consanguinity
7
Q
what are the features of an autosomal dominant disease
A
- vertical transmission
- lack of skipped generations
- equal males and females
- may see reduced penetrance
- may see incomplete dominance
- may see variability in expressivity
8
Q
what is reduced penetrance
A
dont show the phenotype
9
Q
what is genetic heterogeneity
A
different genotypes are associated with the same phenotype
