Genetics Flashcards
G1 phase
- period after cell division and before start of DNA replication
- cells grow and monitor environment to determine whether to initiate another round of cell division
S phase
- period of DNA synthesis
- cells replicate chromosomes
G2 phase
- period between end of DNA replication and start of cell division
- cells check to make sure DNA replicated successfully and make any necessary repairs
M phase
- period of actual cell division
- prophase, metaphase, anaphase, telophase, and cytokinesis
diploid
two copies of each chromosome
haploid
one set of chromosomes
autosomes
chromosomes that do not differ between males and females
sex chromosomes
chromosomes that differ between males and females
euploid
cells with complete number of chromosomes
aneuploid
cells with missing or extra chromosomes
homologous
two copies of a particular chromosome that can have different variants of the same gene
unreplicated chromosome
chromosome with one long strand of DNA double helix
replicated chromosome
chromosome that has been copied and consists of two identical chromatids, each containing one double helix and joined at the centromere
sister chromatids
the two attached, identical copies of a replicated chromosome
mitosis prophase
chromosomes condense; each chromosome consists of a pair of identical sister chromatids joined at the centromere
mitosis metaphase
chromosomes line up at the middle of the cell, along the plane of cell division, pushed and pulled by microtubules of the spindle apparatus
mitosis anaphase
sister chromatids separate and migrate towards opposite ends of the cell
mitosis telophase
chromatids cluster at opposite ends of the cell and begin to decondense
cytokinesis
the membrane pinches in to divide the two daughter cells
Mendel’s Law of Independent Action
all possible combinations of maternal and paternal chromosomes are possible in the two daughter cells
prokaryote genome
usually packed into one circular chromosome consisting of circular DNA molecule of few million base pairs (Mbp)
eukaryote genome
packaged into multiple linear chromosomes, each consisting of a linear DNA molecule of tens or hundreds of Mbp