Genetic Variations in Populations

Question 1

population genetics is study of…

Answer 1

genetic variation in population and frequency of allele and genotypes are maintained or changed over time in a population

Question 2

how to calculate genotype frequency and allele frequency

Answer 2

counting alleles

Question 3

what is a gene pool

Answer 3

collection of alleles of an entire population

Question 4

the hardy weinbergy law applies to what genetics

Answer 4

autosomal loci and X chromosomes in females, not X linked loci in males who only have 1 X chromosome

Question 5

What are the 3 assumptions of Hardy Weinberg Law

Answer 5

1. population large and mating random
2. no new mutations
3. no selection against particular genotypes
4. no significant immigration of individuals

Question 6

PKU affects appro. how many people

Answer 6

1/4500 irish people

Question 7

what does Hardy Weingberg not address

Answer 7

1. allele frequency different in populations
2. some mutant alleles are clearly deleterious

Question 8

Factors that affect HWE

Answer 8

mating is random, allele frequency does not change over time, interaction of genetic drift

Question 9

What deviations causes Hardy-Weinberg Disequilibrum

Answer 9

changes in allele frequency due to mutation, selection or migration

Question 10

Hardy-Weinberg Disequilibrum is

Answer 10

allele and its associated genotype are not in equilibrium

Question 11

how is Hardy-Weinberg Disequilibrum useful

Answer 11

provides clues about pathogenesis or point to historical events that affected allele frequency

Question 12

What factors cause Hardy-Weinberg Disequilibrum

Answer 12

population stratitifaction, assortative mating, consanguinity and inbreeding

Question 13

what is ancestory informative markers

Answer 13

large differences in allele frequency among populations