Genetic Variation Flashcards

1
Q

Causes of GV

A
  1. sexual reproduction- genetic recombination, crossing over of chromosome
  2. mutations- can be passed on if cells that make sperm/eggs have mutations
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2
Q

types of mutations

A

PIGG
1. point inversions (insertions/deletions INDELS)
2. inversions
3. gene duplications
4. genome duplications

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3
Q

point mutaions

A

transitions more common than transversions.
genetic code redundant, some changes will not alter encoded a.a

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4
Q

sickle cell anaemia

A

abnormal beta chains
stick together
deoxygenated RBC

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5
Q

inversions

A

naturally, induced by radiation
heterozygotes prevent crossing over

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6
Q

gene duplications

A

retrotransposition
unequal crossing over
TS- copy and paste (retrotransposon) , cut and paste (DNA transposon) , hundreds around the genome

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7
Q

heterozygous advantage

A
  1. inbreeding depression (bad to be highly homo)
  2. over-dominance (good to be highly hetero)
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8
Q

inbreeding avoidance

A

DEKD out
1. dispersal
2. extra-pair paternity
3. kin recognition + avoidance
4. delayed maturation

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9
Q

dispersal

A

eg white-footed mouse goes away from nest to avoid inbreeding

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10
Q

extra-pair paternity

A

eg superb fairy wrens females mate outside the pair with other males

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11
Q

kin recognition + avoidance

A

eg storm petrels can recognise who is distantly/closely related

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12
Q

delayed maturation

A

eg wolves wont be sexual active until away from mother

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13
Q

over-dominance

A

heterozygotes more fit than homo
eg warfarin resistance in rats
1. homo susceptible rats killed by poison
2. homo rats that were resistant had vitamin K defiency
3. hetero are resistant to poison and have vit k deficiency

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14
Q

local adaptation

A

traits vary geographically
eg biotic/ abiotic
eg clines, change in character over distance and vary body size
eg peppered moths

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