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Genetics Lecture > Genetic Interactions Part 2 > Flashcards

Genetic Interactions Part 2 Flashcards

1
Q

Non-Allelic Gene Interaction

A

Novel Phenotype
Recessive Epistasis
Dominant Epistasis
Complimentary Epistasis
Duplicate Gene

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2
Q

T or F

after the discovery of the computation model of Mendel, there are several instances that DO NOT follow the computation

A

True

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3
Q

the dihybrid testcross was discovered by

A

George Beadle
Edward Tatum
1941

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4
Q

the development of dihybrid testcrosses leads to the idea of

A

modifier genes

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5
Q

these are genes that enhance or inhibit the expression of the other gene.

A

modifier genes

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6
Q

complete dominance at gene pairs (mendelian interaction)

A

novel phenotype

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7
Q

the modifier gene completely nulls, the effect of the other genes if it is recessive.

complete dominance but recessive is epistatic.

A

recessive epistasis

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8
Q

the modifier gene completely nulls, the effect of the other genes if it is dominant.

complete dominance but dominant is epistatic.

A

dominant epistasis

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9
Q

T or F

in dominant epistasis, even if both genes are recessive, the modifier gene is expressed.

A

True

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10
Q

at least one allele of of each gene is dominant.

A

complimentary epistasis

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11
Q

at least one dominant presence in any gene.

A

duplicate gene

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12
Q

There are patterns of inheritance that is highly and/or only dependent on the gene interactions in sex chromosomes. It should be noted that the chances of getting male or female offspring is always 50%.

A

sex-linkage

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13
Q

There are two (2) types of gene interactions in sex-linkage:

A

sex-linked traits
sex-influenced traits

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14
Q

genes controlling the trait can be found in X and Y chromosome.

A

sex-linked trait

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15
Q

gene controlling the trait can be found in autosomal chromosome.

A

sex–influenced traits

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16
Q

described as a graphical representation of distribution and expression of genetic traits or disease among members of interrelated generations.

A

pedigree analysis

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17
Q

Sex- Linked Dominant Traits (Genotype)

X^A X^A
X^A X^a
X^A Y
X^a Y

A

female - affected
female - carrier
male - affected
male - unaffected

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18
Q

Sex- Linked Recessive Traits (Genotype)

X^A X^A
X^A X^a
X^A Y
X^a Y

A

female - unaffected
female - carrier
male - unaffected
male - affected

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19
Q

guess the sex-linked trait of the disorder/disease

Fragile X Syndrome (mental retardation)

A

X-linked dominant

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20
Q

guess the sex-linked trait of the disorder/disease

Vitamin D resistant rickets (soft bone)

A

X-linked dominant

21
Q

guess the sex-linked trait of the disorder/disease

Incontinentia pigmenti (hyperactive apoptosis)

A

X-linked dominant

22
Q

guess the sex-linked trait of the disorder/disease

Aicardi Syndrome (No cerebral hemispheres)

A

X-linked dominant

23
Q

guess the sex-linked trait of the disorder/disease

Hemophilia (no blood clotting)

A

X-linked recessive

24
Q

guess the sex-linked trait of the disorder/disease

Color Blindness (red and green)

A

X-linked recessive

25
Q

guess the sex-linked trait of the disorder/disease

Muscular Dystrophy

A

X-linked recessive

26
Q

guess the sex-linked trait of the disorder/disease

Pattern Baldness

A

X-linked recessive

27
Q

guess the sex-linked trait of the disorder/disease

Hypertrichosis pinnae auris (ear hair)

A

Y-linked (no dominant/recessive)

28
Q

guess the sex-linked trait of the disorder/disease

Determination of sex

A

Y-linked (no dominant/recessive)

29
Q

guess the sex-linked trait of the disorder/disease

Webbed Toes

A

Y-linked (no dominant/recessive)

30
Q

guess the sex-linked trait of the disorder/disease

Ichthyosis hystix (Porcupine or Wood Skin)

A

Y-linked (no dominant/recessive)

31
Q

guess the sex-linked trait of the disorder/disease

Color Blindness (red and green)

A

X-linked recessive

32
Q

guess the sex-linked trait of the disorder/disease

Maternal Optic Neuropathy (degradation of nerve)

A

Mitochondrial-linked

33
Q

guess the sex-linked trait of the disorder/disease

Mitochondrial myopathy (degradation of muscles)

A

Mitochondrial-linked

34
Q

guess the sex-linked trait of the disorder/disease

Leigh Syndrome (Abnormal ATP production)

A

Mitochondrial-linked

35
Q

T or F

X-Linked Dominant Traits

More Female are affected due to the presence 2 X chromosomes.

A

True

36
Q

T or F

X-Linked Dominant Traits

Do not skip generation when expressed.

A

True

37
Q

T or F

X-Linked Dominant Traits

Mode Transmission: MOTHER TO SON and FATHER TO DAUGHTER.

A

False

Mode Transmission: MOTHER TO SON/DAUGHTER and FATHER TO DAUGHTER.

38
Q

T or F

X-Linked Dominant Traits

50% son/daughter of heterozygous mother.

A

True

39
Q

T or F

X-Linked Dominant Traits

If both parents have x-linked heterozygous dominant, all offspring will be positive for x-linked dominant.

A

False

If both parents have x-linked HOMOZYGOUS dominant, all offspring will be positive for x-linked dominant.

40
Q

T or F

X-Linked Recessive Traits

More males are affected due to the presence 2 Y chromosomes.

A

False

More FEMALES are affected due to the presence 2 X chromosomes.

41
Q

T or F

X-Linked Recessive Traits

If both parents have x-linked homozygous dominant, all offspring will be positive for x-linked dominant.

A

True

42
Q
  • The only affected offspring is only males.
  • Mode of Transmission: FATHER TO ALL SONS.
  • It does not skip generation.
A

Y-linked Traits

43
Q
  • All offspring is affected or at risk of acquiring traits.
  • Mode of Transmission: MOTHER TO ALL OFFSPRING.
A

Mitochondrial-Linked Traits

44
Q

guess the common autosomal traits whether which one’s dominant/recessive

a. window’s peak
b. no window’s peak

A

a. dominant
b. recessive

45
Q

guess the common autosomal traits whether which one’s dominant/recessive

a. no cheek dimples
b. cheek dimples

A

a. recessive
b. dominant

46
Q

guess the common autosomal traits whether which one’s dominant/recessive

a. no hitchhiker’s thumb
b. hitchhiker’s thumb

A

a. dominant
b. recessive

47
Q

guess the common autosomal traits whether which one’s dominant/recessive

a. face freckles
b. no face freckles

A

a. dominant
b. recessive

48
Q

guess the common autosomal traits whether which one’s dominant/recessive

a. attached earlobes
b. free earlobes

A

a. recessive
b. dominant

49
Q

guess the common autosomal traits whether which one’s dominant/recessive

a. cleft chin
b. without cleft chin

A

a. dominant
b. recessive

Genetics Lecture (6 decks)

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