Genetic Factors Flashcards

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1
Q

What is MAOA (monoamine oxide A)

A

An enzyme that regulates metabolism of serotonin in the brain

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2
Q

What is the MAOA gene

A

The gene responsible for the activity of the enzyme MAOA in the brain- the low-activity variant of the gene is closely associated with aggressive behaviour

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3
Q

Outline a study which reveals the influence of the MAOA gene on aggression

A

Brunner et al. (1993) found that 28 males in a Dutch family, who had a history of impulsively aggressive behaviour (rape, attempted murder), had abnormally low levels of MAOA and the low-activity variant of the MAOA gene

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4
Q

Describe an additional study which supports the role of the MAOA gene on aggression

A

Mertins et al. (2011) found that high-activity variant of MAOA gene can lead to less aggression

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5
Q

What is the difference between MZ and DZ twins

A

MZ twins share 100% of their genes, whereas DZtwins share 50% of their genes

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6
Q

Which twin study revelas the influence of genes on aggression

A

Coccaro et al. (1997) found concordance rates of physical assault were 50% for MZ twins and 19% for DZ twin and found concordance rates of verbal aggression were 28% for MZ and 7% for DZ twins

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7
Q

Which adoption study reveals the influence of genes on aggression

A

Hutchings and Mednick et al. (1975) found that a significant number of adopted boys in Denmark with criminal convictions had biological parents with convictions for criminal violence

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8
Q

Describe a study which has suggested that aggression is a result of a gene-environment interaction rather than just genes in isolation

A

Caspi et al. (2002) determined that children with low-activity variant of MAOA gene were more likely to show anti-social behaviour, only if they had been maltreated as a child

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9
Q

Why is using different methods to measure aggression an issue

A

Makes it difficult to draw valid conclusions about the role of elf genetic factors if research findings vary depending upon how the aggression is measured

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10
Q

Describe a study which suggests the influence of multiple genes on aggression and not just the MAOA gene

A

Stuart et al. (2014) found males who inflicted IPV were more likely to have the low-activity variant of the MAOA gene and the serotonin transporter gene (5-HTT)

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