Genetic Controversies

Question 1

What is done in a genetics clinic?

Answer 1

• Identify patients with, or at risk of, a genetic condition
• Communicate genetic information in an understandable, non-directive manner
• Offer people recommendations re screening
• Discuss implications of gene testing on themselves and family
• Options re treatment

Question 2

What is an ethical dilemma?

Answer 2

A situation in which a difficult choice has to be made between two courses of action, either of which entails transgressing a moral principle

Question 3

What is Huntington’s Disease?

Answer 3

Neuro degenerative condition

Question 4

What type of inheritance does Huntington’s Disease have?

Answer 4

Autosomal dominant

Question 5

What are the problems with genetic testing for Huntington’s Disease?

Answer 5

• Implications of results being positive or negative- need to be prepared for either result
• Insurances need to be updated prior to testing positive
• Potential impact on self, Family (become carers), work (no longer drive)

Question 6

If a patient doesn’t want to undergo genetic testing for a condition, should their child be allowed to?

Answer 6

Yes

Question 7

What are the 2 main forms of prenatal testing?

Answer 7

Chronic villus sampling

Amniocentesis

Question 8

What risk do Chronic villus sampling and Amniocentesis carry?

Answer 8

Risk of miscarriage

Question 9

What issues would you need to consider after a prenatal test?

Answer 9

Termination of pregnancy

Question 10

What are the 2 main genes associated with breast and ovarian cancer?

Answer 10

BRCA1 and BRCA2

Question 11

What screening is done for breast and ovarian cancer?

Answer 11

Mammography

Question 12

What can be done if someone is found to be a carrier of BRCA1 and BRCA2?

Answer 12

Risk reducing surgery

Prophylactic oophorectomy
Bilateral mastectomy.