genetic basis of Sz - explanation Flashcards
1
Q
what is there a strong risk between?
A
degree of genetic similarity and risk of sz
2
Q
what did gottesman do?
A
a large scale family study finding 9% siblings, 17% fraternal and 48% identical twins had sz
3
Q
what are individual genes associated with?
A
risk of inheritance
4
Q
how is sz polygenic?
A
requires a number of factors to work
5
Q
what did ripke carry out?
A
large study combining all previous data from wide studies - 37,000 compared to 113,000 and 108 separate genetic variations found
