Drug therapy for Sz

Question 1

Antipsychotics?

Answer 1

Taken tablet/syrup form
ST/LT
Function in normal life
Combined with therapies

Question 2

When were typicals developed?

Answer 2

1950’s

Question 3

What is the typical drug?

Answer 3

Chlorpromazine - dosage gradually increased until 1000mg

Question 4

What does typical drug act as?

Answer 4

Antagonist in dopamine system - blocks dopamine receptors

Question 5

What does typical drug reduce?

Answer 5

Hallucinations and normalises positive symptoms

Question 6

How are typical drugs less effective?

Answer 6

Require 75% dopamine receptors to be blocked to be effective

Question 7

When were atypical drugs developed?

Answer 7

1970’s

Question 8

What do atypical drugs improve?

Answer 8

Positive, negative symptoms and cognitive impairment

Question 9

What do atypical drugs do?

Answer 9

Temporary block dopamine receptors - used if other treatments fail

Question 10

What do atypical drugs improve?

Answer 10

Mood and cognitive functioning

Question 11

Risperidone?

Answer 11

1990’s
Effective as reduces side effects
Useful for 2 weeks
Binds strongly