generalitati Flashcards

1
Q

BPOC - definitie

A

boala cronica a cailor respiratorii , obstructyie la flux data de expunerea la fumul de tigara sau alti compusi toxici ( care produc fum)

  • pierderea conexiunilor interalveolare si diminuarea reculului elastic
  • difunctie mucociliara
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2
Q

Nefumatorii cu BPOC - riscuri

A
  • nu au risc mare ptr a dezvolta cancer bronhopulmonar sau comorbiditati cardiovasculare
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3
Q

factori genetici

A
  1. deficitul de alfa1 antitripsina

2. gena codand metaloproteinaza sau glutation S transferaza

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4
Q

factori care influenteaza dezvoltarea plamanilor

A

orice factor care influenteaza dezvoltarea plamanilor in timpul gestatiei sau copilariei
exista corelatie intre greutatea la nastere si infectiile respiratorii in timpul copilariei si VEMS

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5
Q

factori toxici

A
tigari 
pipa 
marijuana
profesii: sculptori , gradinari ,lucratori in depozite ( warehouse ) , 
- air trapping + emfizem 
- lemn 
- balegar animale ( animal dung ) 
- reziduri culturi ( crop residues ) 
- coal ( carbune ) 
- biomasa interioara ( indoor biomass ) - gatit
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6
Q

factori socioeconomici

A
  • risc crescut ptr pacientii saraci

- poluanti de interior si exterior , aglomerare urbana ,nutrie saraca , infectii repetate

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7
Q

Astmul

A
  • risc de 12 ori mai mare de a se asocia cu BPOC ( Tucson )
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8
Q

Bronsita cronica

A
  • in special la tineri se asociaza cu un risc de BPOC

- creste numarul si severitatea exacerbarilor

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9
Q

Infectiile

A
  • cresc riscul BPOC
  • colonizarea cu Pseudomonas creste riscul de spitalizare ptr exacerbari si mortalitatea
  • infectia HIV se asociaza cu BPOC
  • tuberculoza
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