General Onc Flashcards

1
Q

CD10

A

CALLA (common ALL antigen)

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2
Q

CD19

A

B cell antigen

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3
Q

Tdt

A

Mature marker for B cells

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4
Q

MPO

A

Myeloid marker

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5
Q

CD3

A

T cell marker

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6
Q

CD33

A

Myeloid marker

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7
Q

Very High Risk pre-B ALL

A

Age >13
Unfavourable features: CNS positive, hypodiploidy (<44), iAMP21 amplification, MLL gene rearrangement, BCR able positive, induction failure - positive MRD on day 29

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8
Q

Febrile neutropenia criteria

A

Fever over 38.3 or over 38 for one hour

ANC < 1x10^9

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9
Q

Organisms to think about in febrile neutropenia

A

Often none identified,
Gram negs; E. coli, klebsiella, pseudomonas

Gram positives: staph aureus, coag negative staph, pneumococci, streptococci

Fungi- candida

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