General/Local Anesthetics Flashcards

1
Q

What is monitored anesthesia care?

A

Midazolam followed by titrated propofol infusion

Provides anxiolysis, amnesia, and mild sedation

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2
Q

What is conscious sedation?

A

Benzos, opioid analgesics

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3
Q

What reverses benzos?

A

Flumazenil

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4
Q

What reverses opioid analgesics?

A

Nalaxone

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5
Q

What causes deep sedation?

A

Propofol and midazolam

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6
Q

Low blood solubility = ____ onset

A

Fast

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7
Q

Low blood solubility drugs

A

NO, desflurane

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8
Q

High blood solubility drugs

A

Halothane

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9
Q

High MAC% = ____ onset

A

Fast

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10
Q

Low blood:gas coefficient = ___ onset

A

Fast

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11
Q

Anesthesia potency is described by MAC, required to prevent response to surgical incision

A

response to surgical stimulation in 50% of subjects

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12
Q

All inhaled anesthetics can _____ right arterial pressure in dose-related manner, caused by depressed myocardial function

A

increase

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13
Q

Inhaled anesthetics

A
Desflurane
Enflurane
Halothan
Isoflurane
NO
Sevoflurane
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14
Q

Enflurane side effect

A

Renal toxicity

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15
Q

Halothane side effect

A

hepatitis

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16
Q

Sevoflurane side effect

A

Renal toxicity

17
Q

IV anesthetics

A
Diazepam
Etomidate
Fentanyl
Ketamine
Midazolam
Propofol
18
Q

Etomidate side effect

A

Decreases steroidogenesis, adrenocortical suppression via inhibiting 11B-hydroxylase

19
Q

Fentanyl

A

Balanced anesthesia and conscious sedation

20
Q

Ketamine side effect

A

Psychotic hallucinations, HTN, tachy

21
Q

Midazolam reversed by

A

Flumazenil

22
Q

Propofol

A

Causes hypotension and anti-emetic effects

23
Q

Propofol MOA

A

Targets GABA-A receptor and potentiates Cl- current

Decreases blood pressure

24
Q

What is an ester local AE?

A

Procaine

25
Q

What is an amide local AE?

A

Lidocaine

26
Q

Benzocaine

A

surface use only

Derm conditions, hemorrhoids, premature ejaculation, lube

27
Q

Bupivacaine

A

Cardiotoxic

Sensory block

28
Q

Dibucaine

A

Used only as topical cream on skin

29
Q

Lidocaine

A

CNS toxicity

Alternative to ester type anesthetic

30
Q

Procaine

A

Slower onset, shorter duration of action

Used for infiltration anesthesia

31
Q

Procaine metabolized by

A

Para-aminobenzoic acid