General hypothalamus Flashcards
Where is the hypothalamus located?
Basal diencephalon, below thalamus
Thermoregulation:
Anterior vs Posterior hypothalamus?
Lesion?
Anterior hypothalamus = heat dissipation
lesion = hyperthermia
Posterior hypothalamus = heat conservation
lesion = poikilothermia *a posterior lesion damages efferents from both posterior and anterior regions
What does the hypothalamus do?
HEAL Homeostasis Endocrine Autonomic Limbic
What controls autonomic and endocrine activity?
Efferents
What are the 2 important two-way circuits? What specific parts of each?
Forebrain - amygdala and hippocampus
Brainstem - arousal centers, reticular formation, monoamine groups
What is the limbic system? What are the parts/which parts regulate what?
interconnected neural structures that regulate HOME Homeostasis - hypothalamus Olfaction - olfactory cortex Memory - hippocampus Emotion - amygdala
Whats between the mammillary bodies and the optic nerve (looking at the ventral surface of the brain)
Tuber cinereum
The hypothalamus is surrounded by what structures?
Lamina terminalis Optic chiasm Infundibulum Mammillary bodies Thalamus
What three areas is the hypothalamus divided into?
Periventricular (3rd ventricle)
Medial
Lateral
Which hypothalamic division has the most diffuse organization?
Lateral part
The periventricular area nucleus releases what 2 hormones? What are their pathways?
- TRH - TSH - T3, T4 - energy balance
2. somatostatin inhibits release of GH
The supraoptic nucleus (medial area) releases what two hormones? What is their pathway?
- vasopression (ADH) - water retention in kidney
2. oxytocin - uterine contraction and milk letdown
The paraventricular nucleus (medial area) releases what 2 hormones? Pathway?
- vasopressin (ADH) - water retention in the kidney
2. oxytocin - uterine contraction and milk letdown
The suprachiasmatic nucleus (medial area) releases what hormones? Pathway?
Cortisol and melatonin
It is the master pathway of circadian rhythm
* receives direct input from retina
Arcuate nucleus & ventromedial nucleus (medial area)
+ lateral preoptic nucleus and lateral hypothalamic nucleus (lateral area) do what?
Regulate hunger and satiety (stimulates adipocytes to release leptin)