Gall Limbic 3 Flashcards
hippocampus is the site of new _________ ___________ formation
declarative memory
Hippo output to mammillary bodies is relayed through?
subiculum
Lay out the Papez circuit
Mammillary bodies to the anterior thalamus to the cingulate cortex to the entorhinal cortex (inputs/outputs via neocortex) to hippocampus to subiculum back to mammillary bodies
The Papez circuit allows for what 2 connections?
Arousal centers/brain stem to influence memory formation in the hippocampus
Cortex to influence hypothalamic and autonomic functions
area of memory formation vs area of memory storage? Do they communicate via Papez?
Hippocampus, neocortex
yes
Septal nuclei communicate with subiculum and anterior thalamus via? What important connection does this make?
The fornix
Brainstem arousal centers to hippocampus
What does the fornix separate?
Medial and lateral hypothalamus
Septal nuclei
The medial septum projects _________ neurons to the hippocampus
Cholinergic
Septal nuclei
The lateral septum receives axons from __________
hippocampus
The papez circuit allows for higher cortical areas to influence ________ activities of the hypothalamus and _________ activities of the brainstem
endocrine, autonomic
entorhinal/piriform cortices are the first to degenerate in what disease? What is it thought to disconnect?
AD
Though to disconnect the hippocampus
Damage to cingulate/frontal cortex causes what affect?
Flat affect
What is Korsakoff’s syndrome?
Thiamine deficiency causing confabulatory amnesia
Involves midline thalamus damage
CA1, pyramidal cells are most vulernable to what? Responsible for what after heart attack?
Ischemia
exhibits neuronal cell death with stroke, heart attack
Short term memory loss after heart attack
hippocampal lesion causes loss of what type of memory formation
declaritive
