General CSF Questions Flashcards
What is the Henderson-Hasselbalch Equation?
What is the bicarbonate buffering system equation?
What indicates metabolic acidosis?
Abnormal [HCO3-]
What indicates respiratory acidosis?
Abnormal [CO2]
What is Hsp70 and what does it do?
Hsp70 is a molecular chaperone
It prevents aggregation of hydrophobic regions and allows for spontanous folding
What is GroEL & GroES?
GroEL & GroES is a chaperonin complex
It provides a hydrophilic folding chamber to induce protein folding
Name two general protein domains/motifs and give an example of each
- Coiled-coil (i.e. Leucine zipper)
- Zinc finger (i.e. transcription factors)
What three amino acids can be phosphorylated?
Tyrosine, serine, and threonine
Name the five types of RNA, from most common to least
rRNA
tRNA
mRNA
Small nuclear RNA
Small nucleolar RNA
Describe the difference in linkage between glycogen and cellulose
Which one cannot be digested?
Glycogen has alpha(1,4) linkages and can be digested
Cellulose has beta(1,4) linkages and cannot be digested
What is an N-linked glycoprotein?
The sugar bonds to the side chain of asparagine
What is an O-linked glycoprotein?
The sugar bonds to the side chain of serine or threonine
What is a cerebroside?
A glycolipid with a single sugar for a head-group
What is a ganglioside?
A glycolipid with a complex sugar for a head-group
What is the difference between flippases and floppases?
Flippases: out to in
Floppases: in to out
Both move membrane lipids against their gradients
