DNA Replication Flashcards

1
Q

Prokaryotic origin complex

A

DnaA

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2
Q

Eukaryotic origin complex

A

ORC & cdt1

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3
Q

Prokaryotic primer

A

DnaG

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4
Q

Eukaryotic primer

A

Pol alpha primase

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5
Q

Prokaryotic helicase loader

A

DnaC

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6
Q

Eukaryotic helicase loader

A

None

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7
Q

Prokaryotic helicase

A

DnaB

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8
Q

Eukaryotic helicase

A

CMG complex

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9
Q

Prokaryotic ssDNA binding

A

SSBPs

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10
Q

Eukaryotic ssDNA binding

A

RPA

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11
Q

Prokaryotic negative supercoiler

A

Topoisomerase & DNA gyrase

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12
Q

Eukaryotic negative supercoiler

A

Topoisomerase

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13
Q

Prokaryotic clamp loader

A

Gamma subunit of pol III

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14
Q

Eukaryotic clamp loader

A

RFC

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15
Q

Prokaryotic sliding clamp

A

Beta subunit of pol III

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16
Q

Eukaryotic sliding clamp

A

PCNA

17
Q

Prokaryotic polymerase

A

Pol III

18
Q

Eukaryotic polymerases

A

Pol epsilon - leading

Pol delta - lagging

19
Q

Prokaryotic removal and replacement of primer

A

Pol I, RNase H, & ligase

20
Q

Eukaryotic removal and replacement of primer

A

RNase H, FEN1, DNA2, Pol delta, & ligase

21
Q

Prokaryotic termination

A

Tus binding to Ter sequences

22
Q

Eukaryotic termination

A

Telomerase