General Flashcards

1
Q

What does the Michaelis menten equation describe

A

How rxn velocity varies with substrate concentration

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2
Q

MM kinetics follow a ___ curve?

A

Hyperbolic curve

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3
Q

What are factors wc can affect the rxn rate

A

Substrate conc, temp, pH

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4
Q

Lineweaver burke plot is used for

A

Calculated Km and Vmax; determines mechanism of action of enzyme inhibitors

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5
Q

Precursor of arachidonic acid

A

Linoleic acid

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6
Q

Alcohol+ diacylglycerol/ spingosine via phosphodiester bond

A

Phospholipid

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7
Q

Spingosine and Fatty acid

A

Ceramide

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8
Q

Ceramide and gluctose or galactose

A

Cerebroside

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9
Q

Ceramide and oligosaccharide

A

Globosidr

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10
Q

Ceramide and N acetylneuramic acid

A

Ganglioside

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11
Q

Ceramide and sulfated galactose

A

Sulfatides

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12
Q

3 main kinds of eicosanoids

A

Porstaglandin, thromboxane, leukotrienes

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13
Q

Amino acid structure

A

Caboxyl, amino group, unique side chain

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14
Q

Smallest amino acid

A

Glycine

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15
Q

Largest amino acid

A

Tryptophan

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16
Q

Amino acid used in the 1st step of heme synthesis

A

Glycine

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17
Q

Major inhbitory NT in spinal cord

A

Glycine

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18
Q

AA that carries N from peripheral tissues to the liver

A

Alanine

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19
Q

Precuror of niacin, serotonin and melatonin

A

Tryptophan

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20
Q

Precursor for homocysteine

A

Methionine

21
Q

An imino acid

A

Proline

22
Q

To cysteines form

A

Custine

23
Q

Major carrier of nitrogen from the peripheral tissues to the liver

A

Glutamine

24
Q

Precursor for GABA and glutathione

A

Glutamate

25
Q

Used in diagnosis of folic acid deficiency

A

N- formiminoglutamate excretion test

26
Q

Precursor of creatinine, urea and nitric oxide

A

Arginine

27
Q

All amino acids are chiral except for

A

Glycine

28
Q

Chemical compound that has a total net charge of zero

A

Zeitteriob

29
Q

Condotionally non essential amino acids

A

Arginine, histidine

30
Q

Most common secondary structure of proteins

A

Alpha helix

31
Q

Minor transporternof hgb in bloof

A

Hemoglobin (carbaminoHb)

32
Q

HgB form with high oxygen affinity? Taut or Relaxed

A

Relaxed

33
Q

Heme protein in heart and skeletal muscle

A

Myoglobib

34
Q

Curve followed by Hgb

A

Sigmoidal

35
Q

Deoxy form of HgB has a greater affinity for protons than does oxyhemoglobin

A

Bohr effect

36
Q

Stabilizes T structure of Hgb by forming additional salt bridges that must be broken prior to conversion to the R state

A

2,3 BPG

37
Q

Oxidized form of Hgb (Fe3)

A

Methemoglobin

38
Q

Chocolate cyanosis

A

Methemoglobinemia

39
Q

Most abundant protein in body

A

Collagen

40
Q

Most common form of collagen

A

Type I

41
Q

Amino acid sequence of collagen

A

Gly-X-Y ; x: proline= kinking; y: hydroxyproline or hydroxylysine

42
Q

HCl is produced by what cells

A

Parietal cells

43
Q

Pepsinogen is produced by

A

Chief cells

44
Q

All amino acids must transfer their amino groups to a ketoglutarate to from GLUTAMATE except

A

Lysine and threonine

45
Q

Coenzyme in transamination

A

Vit B6

46
Q

Removal of excess N from peripheral tissues is via

A

glutamine, alanine, glutaminase

47
Q

Also known as the Krebs Henseleit Cycle/ Ornithine cycle

A

Urea cycle

48
Q

How do enzymes work

A

Lower free energy of activation