general Flashcards

0
Q

Antidote for salicytes

A

NaHCO3, alkalinize

dialysis

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1
Q

antidote for acetaminophen

A

N-acetylcysteine

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2
Q

Amphetamines Antidote

A

NH4Cl,acidify urine

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3
Q

Antidote for Acetylcholinesterase inhibitors

organophsphates

A

Atropine

pralidoxime

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4
Q

Antidote for Antimuscarinic, anticholinergic agents

A

Physostigmine salicylate

control hyperthermia

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5
Q

Beta-blocker

A

Glucagon

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6
Q

Digitalis antidote

A

Normalize K+
Lidocaine
Anti-dig Fab fragment
Mg2+(KLAM)

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7
Q

Antidote for Iron

A

Deferoxamine

deferasirox

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8
Q

Lead antidote

A

CaEDTA
dimercaparol
succimer
penicillamine

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9
Q

Antidote for Mercury, arsenic, gold

A

Dimercaprol(BAL)

succimer

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10
Q

Antidote Copper, arsenic, gold

A

Penicillamine

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11
Q

Antidote cyanide

A

Nitrite+thiosulfate

hydroxocobalamine

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12
Q

Antidote for methemoglobin

A

methlene blue

vitamin C

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13
Q

CO antidote

A

100%O2

hyperbaric O2

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14
Q

Antidote for
Methanol
ethylene glycol

A

Fomepizole>ethanol

dialysis

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15
Q

Antidote for

Opioids

A

Naloxone

naltrexone

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16
Q

Antidote:

Benzodiazepine

A

Flumazenil

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17
Q

Antidote for TCA

A

NaHCO3

plasma alkalinization

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18
Q

antidote for heparin

A

Protamine

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19
Q

antidote for warfain

A

vitamin K

fresh frozen plasma

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20
Q

Antidote for tPA, streptokinase, urokinase

A

aminocapronic acid

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21
Q

antidote for theophylline

A

Beta-blocker

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22
Q

Drugs that lead to coronary vasospasm

A

cocaine
sumatriptan
ergot alkaloid

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23
Q

Drug reaction

cutaneous flushing

A

vancomycin
adenosine
niacin
Ca2+ channel blocker

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24
Q

Drug reaction

Dilated cardiomyopathy

A

Doxorubicin(adriamycin)

daunorubicin

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25
Q

Drug reaction

Torsades de pointes

A
Class III (sotalol)
class iA (quinidine)
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26
Q

increase QT

increase AP duration

A
class IA
K+channel blocker
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27
Q

decrease AP

A

Class IB

Lidocaine Mexiletine Tocainide

28
Q

agranulocytosis

A
clozapine
carbamazepine
colchicine
Propylthiouracil
methimazole
dapsone
agranulocytosis could certainly cause pretty major damage
29
Q

aplasic anemia

A
chloramphenicol
benzene
NSAID
propylthiouracil
methimazole
30
Q

Direct Coombs + hemolytic anemia

A

Mthyldopa

penicillin

31
Q

Gray baby sndrome

A

choloramhenicol

32
Q

hemolysis in G6PD-deficient patients

A
isoniazid
sulonamides
primaquine
aspirin
ibuprofen
nitrofurantoin
33
Q

megaloblastic anemia

A

phenytoin
methotrexate
sulfa drugs

34
Q

thrombotic complication

A

OCP

35
Q

cough

A

ACEI

36
Q

pulmonary fibrosis

A

bleomycin
amiodarone
busulfan

37
Q

Acute cholestatic hepatitis, jaundice

A

Erythromycin

38
Q

Focal to massive hepatic necrosis

A

Halothane
Amanita phalloides
Valproic acid
Acetaminophen

39
Q

hepatitis

A

INH

40
Q

pseudomembranous colitis

A

clindamycin

ampicillin

41
Q

Adrenocortical insufficiency

A

glucocorticol withdrawal

HPA suppression

42
Q

gynecomastia

A
Spironolactone
Digitalis
Cimetidine
chronic Alcohol use
Estrogen
Ketoconazole
43
Q

Hot flashes

A

Tamoxifen

clomiphene

44
Q

hyperglycemia

A
Niacin
tacrolimus
protease inhibitor
HCTZ
corticosteroids
45
Q

Hypothyroidism

A

Lithium
amiodarone
sulfonamides

46
Q

Fat distrubution

A

Glucocorticoids

protease inhibitor

47
Q

Gingival hyperplasia

A

phenytoin

verapamil

48
Q

Gout

A

Furosemide
thiazide
niacin
cyclosporine

49
Q

myopathies

A
fibrates
niacin
colchicine
hydroxychloroquine
IFN-alpha
Penicillamine
Statins
Glucocorticoids
50
Q

Osteoporosis

A

corticosteroids

heparin

51
Q

photosensitivity

A

sulfonamide
amiodarone
tetracycline

52
Q

Rash

stevens-Johnson

A
Penicillin
Ethosuximide
carbamazepine
sulfa drug
Lamotrigine
Allopurinol
Phenytoin
Phenobarbital
53
Q

SLE-like syndrome

A

Hydralazine
INH
Procainamide
phenytoin

54
Q

teeth abnormality in kids

A

tetracycline

55
Q

Tendonitis
tendon rupture
cartilage damage

A

Fluoroquinolones

56
Q

Diabetes insipidus

A

Lithium

demeclocycline

57
Q

Fanconi syndrome

A

Expired tetracycline

58
Q

Hemorrhagic cystitis

A

cyelophosphamide
ifosfamide
coadministering with mesna

59
Q

intersititial nephritis

A

methcillin
NSAID
furosemide

60
Q

SIADH

A

Carbamazepine

cyclophosphamide

61
Q

Cinchonism

A

Quinidine

Quinine

62
Q

parkinson-like syndrome

A

Antipsychotic
reserpine
metoclopramide

63
Q

seizure

A
Isoniazid
Bupropion
Imipenem/cilastatin
tramadol
enflurane
metoclopramide
64
Q

Taedive dyskinesia

A

antipsychotics

65
Q

Antimuscarinic

A

Atropine
TCAs
H1-blockers
neuroleptic

66
Q

Disulfiram like reaction

A

Metronidazole
certain cephalosporins
procarbazine
1st gen sulfonylurea

67
Q

Nephrotoxicity

A

aminoplycoside
vacomycins
loop diuretics
cisplatin