Gene Therapy Steps Flashcards
Alleles can be delivered via _ that carry DNA into the patients own cells
Viruses
- Cells harvested
Ex vivo is carrying out gene therapy on cells _
Outside the body
- Cells harvested
Ex vivo reduces risk they the body’s immmune system will produce _
Inflammation
- Virus disabled
Viruses own genetic material is _ or _
Removed
Deactivated
- Virus disabled
_ or _ in virus is removed or deactivated
DNA
RNA
- Gene inserted
Healthy allele inserted in _
Virus’s protein coat
- Virus added to cell
Virus introduced into the cell taken from _
Patient
- Virus added to cell
Once inside, virus will _
Insert dna in cell’s genome
- Healthy gene inserted into cells
This kind of treatment is often used for _ such as skin and blood cells
Dividing cells
- Healthy gene inserted into cell
The gene is _ before being introduced into body
Copied to daughter cells
- Cells inserted into body
Cells, now containing _ inserted into patient
Healthy allele
- Cells containing healthy allele inserted as single injection into the _
Tissue affected by the disorder
- Protein production
Now correct _ can be made and disease diminished or cured
Protein
In some therapies, only one _ is required
Treatment
