Aptamer Steps

Question 1

1. Sequence

An aptamer is a sequence of _

Answer 1

Single stranded DNA or RNA

Question 2

1. Sequence

Researchers create millions of possible sequences until one _

Answer 2

Folds to produce desired shape

Question 3

2. 3D shape

Same forces between bases that cause them to form double helix also _

Answer 3

Folds them into 3D shape

(Just as protein)

Question 4

3. Binding to target

Researchers attach _ to the aptamer they create

Answer 4

Drug molecule

Question 5

3. Binding to target

When aptamer with drub molecule enters body, it attaches to specific part of _ or _ but nothing else

Answer 5

Target pathogen

Diseased cell