GENE THERAPY AND NANO WORLD Flashcards
- The body’s “instruction manual. ”
- Tell your body how to work.
- They live in almost every cell in your body, and they’re made up of a chemical called DNA
GENES
Every unique gene has a DNA sequence that is considered “normal” for that particular gene. But, sometimes this DNA sequence is different than usual
GENE VARIANT
BLUEPRINT TO OUR BODY
GENES
CAN FILL IN MISSING PARTS OR CORRECT ERRORS IN THE DRAWINGS
GENE THERAPY
- The use of genetic material to treat or prevent disease.
- Aims to address the underlying cause of disease, such as changes in our genes.
GENE THERAPY
is like a package used to deliver a specific message.
VECTOR
______ can be used as vectors because they have evolved to be very good at getting into cells.
VIRUSES
- Transfer of a section of DNA to any cell of the body that DOESN’T produce sperm or eggs.
- Effects of gene therapy will not be passed onto the patient’s children.
SOMATIC GENE THERAPY
2 TYPES OF SOMATIC GENE THERAPY
EX-VIVO AND IN-VIVO
TWO DIFFERENT TYPES OF GENE THERAPY DEPENDING ON WHICH TYPES OF CELLS ARE TREATED
SOMATIC GENE THERAPY AND GERMLINE GENE THERAPY
TREATMENT REMOVES THE PERSON’S OWN CELLS AND DELIVERS THE GENETIC MATERIAL TO THESE CELLS OUTSIDE THE BODY. THE MODIFIED CELLS ARE THEN RETURNED TO THE BODY
EX-VIVO
TREATMENT MEANS THE GENETIC MATERIAL IS DELIVERED DIRECTLY INTO THE PERSON, SUCH AS THROUGH AN INJECTION
IN-VIVO
- Transfer of a section of DNA to cells that produce eggs or sperm.
- Effects of gene therapy will be passed onto the patient’s children and subsequent generations.
GERMLINE GENE THERAPY
TECHNIQUES FOR CARRYING OUT GENE THERAPY
GENE AUGMENTATION THERAPY
GENE INHIBITION THERAPY
KILLING OF SPECIFIC CELLS
SOME TYPES OF GENE THERAPY PRODUCTS:
- PLASMID DNA
- VIRAL VECTORS
- BACTERIAL VECTORS
- HUMAN GENE EDITING TECHNOLOGY
- PATIENTS DERIVED CELLULAR GENE THERAPY PRODUCTS
