Gene Splicing and Cancer Flashcards
How many base pairs of the human genome encodes proteins?
3200 Mbp
How many genes do E. coli have?
4400 genes
How many base pairs per protein reading frame in E. coli?
1000 base pairs
How many base pairs of the E. coli genome encodes proteins?
4.6 Mbp
For multicellular organisms, is there a link between complexity and the number of genes?
No
What explains the complexity of multicellular organisms if it is not down to the number of genes?
Alternative splicing
Allows organisms to produce many more proteins (as many as 100 thousand)
How many genes do yeast have?
6000
How many genes do fruit flies have?
14,000
How many genes does the nematode have?
20,000
How many genes does the brine shrimp have?
33,000
How many genes does the apple have?
57,000
How many genes do humans have?
20,600
Splicing is a delicate balance between what?
Desirable and undesirable outcomes