Gene Expression - Lecture 1 Flashcards
What are constitutively expressed genes?
genes that are continuously expressed in most cells
What kind of gene is the trp operon?
repressible gene
What is an operon?
a group of structural genes that control transcription
What is a regulatory gene?
encodes regulatory protein that can bind to the operator side to regulate mRNA transcription
What are negative inducible operons?
when the regulator protein binds only to the operator which prevents RNA polymerase from transcribing
What occurs in a negative inducible operon when there is no inducer present?
the operon doesn’t need to be expressed so it is shut off, regulatory protein binds to operator DNA sequence and blocks operon so transcription do not occur
What occurs in a negative inducible operon when there is an inducer present?
the inducer binds to regulator so the regulator cannot bind to operator so transcription takes place
What are negative repressible operons?
occurs when a regulator protein needs to be activated by a product before it can bind to the operon to prevent transcription
What occurs in a negative inducible operon when no product U is present?
regulator protein does not bind to operator and transcription takes place
What occurs in a negative inducible operon when product U is present?
product U binds to regulator protein so transcription cannot occur
What is a positive control operon?
activator binds to DNA and helps RNA polymerase with transcription