Geeky medics Facts Flashcards

1
Q

Treatment of angina
- even if morphine given

A

By sublingual administration using aerosol spray

Adult

400–800 micrograms, to be administered under the tongue and then close mouth, dose may be repeated at 5 minute intervals if required; seek urgent medical attention if symptoms have not resolved 5 minutes after the second dose, or earlier if the pain is intensifying or the person is unwell.

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2
Q

Treatment of Pituitary diabetes insipidus

A
  1. Vasopressin, intramuscular injection, or by subcutaneous injection, 5–20 units every 4 hours, dose expressed as argipressin.

or

  1. Desmopressin 100 micrograms, Oral (PO), Three times daily (TDS).
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3
Q

Acute otitis media - paediatric dose

A

Amoxicillin, Oral (PO).

Child 1–11 months
125 mg 3 times a day for 5–7 days.

Child 1–4 years
250 mg 3 times a day for 5–7 days.

Child 5–17 years
500 mg 3 times a day for 5–7 days.

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4
Q

Naproxen Advice

A

Naproxen should be stopped if diarrhoea and vomiting or signs of infection occur - NSAID Sick day rules = reduces risk of AKI, in dehydrating illnesses.

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5
Q

QT prolongation search strategy:

A

“Appendix 1”, ctrl F “QT”, or “prolong QT” - finds the entire table, or ctrl F each drug at a time and see what table its under and do this for all listed

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6
Q

Fungal nail infection
Oral drug:
Monitoring:

A

Liver function tests:
Monitor hepatic function before treatment and then periodically after 4–6 weeks of treatment—discontinue if abnormalities in liver function tests.

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7
Q

Migraine - Acute tx

A
  1. Aspirin and Ibuprofen
  2. Sumatriptan 50 mg, oral (PO)
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8
Q

New rash, not painful, itchy, works at a nursery, vesicular, around mouth and nose only, vesicles present are small, some have ruptured, leaving golden-brown crust on an erythematous base
Dx:
Tx:

A

Impetigo
Hydrogen peroxide 1%, 2-3 times daily, Topical (TOP), 5-7 days.

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9
Q

Gentamicin: If the pre-dose (‘trough’) concentration is high…

A

the interval between doses must be increased.

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10
Q

Gentamicin: If the post-dose (‘peak’) concentration is high…

A

the dose must be decreased.

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11
Q

Paeds: For eye related ‘allergic’ or hay fever like treatment search:

A

Eye, allergy and inflammation….
Eye drops:

E.g.
Sodium cromoglicate 2%, 1 drop to each eye, ocular, QDS four times daily.

Eye drops containing antihistamines, such as antazoline with xylometazoline, azelastine hydrochloride, epinastine hydrochloride, ketotifen, and olopatadine, can be used for allergic conjunctivitis.

Sodium cromoglicate and nedocromil sodium eye drops may be useful for vernal keratoconjunctivitis and other allergic forms of conjunctivitis.

Lodoxamide eye drops are used for allergic conjunctival conditions including seasonal allergic conjunctivitis.

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12
Q

Primary hypothyroidism Tx:

A

Levothyroxine: Oral
Adult
Initially 1.6 micrograms/kg once daily, adjusted according to response, round dose to the nearest 25 micrograms, dose to be taken preferably 30–60 minutes before breakfast, caffeine-containing liquids (e.g. coffee, tea), or other medication.

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13
Q

Sepsis - search strategy: and tx

A

Search: ‘infections’, or ‘Blood infections, antibacterial therapy’

  1. Piperacillin with Tazobactam
    Intravenous infusion
    Adult
    4.5 g every 8 hours; increased if necessary to 4.5 g every 6 hours, increased frequency may be used for severe infections.
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14
Q

Search strategy: information giving about stopping medications if certain symptoms occur —-

A

Ctrl F: ‘Advice’ or ‘Patient and Carer Advice’ - section. rather than looking at SEs!

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15
Q

For Chicken pox treatment -
search strategy and tx:
‘Aciclovir’
or ‘Herpes’

A

-> Herpesvirus infections
Treatment summary
-> Drug choice for treatment -> Aciclovir

Post-exposure prophylaxis of varicella zoster infection, preg/non-preg

Aciclovir, Oral (PO)
Adult
800 mg 4 times a day for 7 days, start course on day 7 after exposure; if the patient presents after this, the course may be started up to day 14 after exposure.

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16
Q

Tension headache - unsearchable so just learn the treatment.

A

1g Paracetamol PO Oral

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17
Q

Statin monitoring advice:
> 3 times upper limit -?
<3 times upper limit -?

A

> 3 stop, < 3 continue
Liver function
Liver enzymes should be measured before treatment, and repeated within 3 months and at 12 months of starting treatment, unless indicated at other times by signs or symptoms suggestive of hepatotoxicity. Those with serum transaminases that are raised, but less than 3 times the upper limit of the reference range, should not be routinely excluded from statin therapy. Those with serum transaminases of more than 3 times the upper limit of the reference range should discontinue statin therapy. A

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18
Q

Patient collapses post ‘any medicine’ + wheezy and breathless -?

A

Anaphylaxis - Adrenaline
ctrl F: -‘anaphylaxis’
Adult
Hydrocortisone, Intramuscular, 500 micrograms, using adrenaline 1 in 1000 (1 mg/mL) injection, repeat dose after 5 minutes if no response; if life-threatening features persist, further doses can be given every 5 minutes until specialist critical care available, to be injected preferably into the anterolateral aspect of the middle third of the thigh.

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19
Q

Omeprazole rare but possible electrolyte imbalance side effect:

A

Hyponatraemia

21
Q

What are the different treatment pathways in for COPD?
- search strategy

A

COPD
1. Stable
- with asthmatic
- ctrl F: ‘with as’

  • without asthmatic
  • ctrl F: ‘without as’
  1. Exacerbation
22
Q

What does COPD with asthmatic features suggest?

A

Steroid responsiveness, hence ICS part of treatment plan

23
Q

Benign Prostatic Hyperplasia

A

Acute tx: (urinary retention)
Tamsulosin hydrochloride, 400 micrograms, oral (PO), once.

Long tx: Finasteride 5 mg oral, OD, takes 6 months to become effective

24
Q

Acute urinary retention tx:

A

Acute retention is painful and requires immediate treatment by catheterisation. Before the catheter is removed an alpha-adrenoceptor blocker (such as alfuzosin hydrochloride, doxazosin, tamsulosin hydrochloride, prazosin, indoramin or terazosin) should be given for at least two days to manage acute urinary retention A .

25
ED px, collapse, palpitations, several episodes, - polymorphic ventricular tachycardia?
QT prolongation: search - Appendix 1 ctrl F named drugs in answer stem: - Fluconazole - Citalopram - Ranolazine
26
Worsens heart failure: contraindicated
1. Diltiazem hydrochloride 2. Prednisolone
27
Paracetamol frequency
6 hourly - NOT 4 hourly! - this is a prescribing error, without noting (4g max dose in 24 hours)
28
Respiratory depression, pupil size 1 bilaterally (pinpoint), ABGs acidosis, snoring loudly, unresponsive - toxicity?
Opioid - dihydrocodeine 30mg oral BD - co-codamol 8/500 mg oral, two tables QDS
29
Skin, swelling and erythema, +/- bite
Think Cellulitis: Oral or Intravenous first line: Flucloxacillin. Alternative in penicillin allergy or flucloxacillin unsuitable: clarithromycin, oral erythromycin (in pregnancy), or oral doxycycline. Oral or Intravenous first line if infection near the eyes or nose: Co-amoxiclav. Alternative in penicillin allergy or co-amoxiclav unsuitable: clarithromycin with metronidazole.
30
Agitated, acutely confused, Parkinson's Disease patient tx:
Haloperidol: avoid in PD Lorazepam: safe
31
Gentamicin peak and trough level explanation
For multiple daily dose regimens, blood samples should be taken approximately 1 hour after intramuscular or intravenous administration (‘peak’ concentration) and also just before the next dose (‘trough’ concentration). If the pre-dose (‘trough’) concentration is high, the interval between doses must be increased. If the post-dose (‘peak’) concentration is high, the dose must be decreased.
32
if mention of mineralocorticoid steroids and glucocorticoid steroids,,,,
search steroid: go to corticosteroids, general use, and ctrl F or tab search Side Effects ... psychiatric reactions
33
Methotrexate dosing error: Daily: Weekly:
Max weekly dose is 30 mg!, but ranges e.g 15 mg weekly. Weekly: 7.5 mg, ....... NOT 75!!
34
Beneficial therapeutic monitoring after 7 days of Digoxin in AF px
Heart rate. Digoxin should reduce the heart rate to control AF and improve symptoms
35
Migraine prevention
Betablocker: Propranolol 80 mg daily divided doses... 20 mg QDS 40 mg BD milligrams oral
36
Prevention of Pre-eclampsia from 12 weeks of pregnancy....
ASPIRIN 75 milligrams, oral, daily Pregnant females are at high risk of developing pre-eclampsia if they have chronic kidney disease, diabetes mellitus, autoimmune disease, chronic hypertension, or if they have had hypertension during a previous pregnancy; these females are advised to take aspirin [unlicensed indication] from week 12 of pregnancy until the baby is born.
37
Trigeminal neuralgia...
Search: Neuropathic pain, ctrl F trigeminal.... Carbamazepine 100 mg PO OD
38
Fournier's Gangrene, necrotising fasciitis, affects perineal, genital, or perianal, scrotal regions. Rare Side Effect of?
SGLT2 inhibitors -Dapagliflozin, needs to be discontinued
39
Adjunct to diet for primary hypercholesterolaemia or combined (mixed) hyperlipidaemias in patients who have not responded adequately to dietary control ... tx?
Atorvastatin: By mouth Adult 10–40 mg daily, dose to be taken at night, dose to be adjusted at intervals of at least 4 weeks. Prevention of cardiovascular events
40
Stroke
<4.5 hrs- alteplase 900 mg/kg, max 90 mg, intravenous >4.5 hrs - Aspirin 300 mg, rectal if no safe swallow, oral if swallow is safe
41
Side effect of dyspnoea, shortness of breath
likely cause is Ticagrelor, this is different from respiratory depression, which isnt described as SOB so dont be confused by putting morphine
42
Peptic ulcer causing drugs as side effects.... epigastric pain, worse after eating
1. alendronic acid 2. prednisolone 3. naproxen
43
vaginal candidiasis
white vaginal discharge, vulval itching, STI aquired, UTI 3 weeks ago Abx, cheese-like white discharge. tx - fluconazole 150 milligrams oral PO
44
Myasthenia gravis
Pyridostigmine bromide is less powerful and slower in action than neostigmine but it has a longer duration of action. It is preferable to neostigmine
45
Surgical DVT prophylaxis
A low molecular weight heparin (enoxaparin, 40 milligrams, SC, OD, 28 days) is suitable in all types of general and orthopaedic surgery; heparin (unfractionated) is preferred in patients with renal impairment. Fondaparinux sodium is an option for patients undergoing abdominal, bariatric, thoracic or cardiac surgery, or for patients with lower limb immobilisation or fragility fractures of the pelvis, hip or proximal femur. A Pharmacological prophylaxis in general surgery should usually continue for at least 7 days post-surgery, or until sufficient mobility has been re-established. Pharmacological prophylaxis should be extended to 28 days after major cancer surgery in the abdomen, and to 30 days in spinal surgery.
46