Gastrulation Mechanisms (Trans 7) Flashcards
Inclusion of migratory apparatus for cell motility
Cell Polarity
8 mechanisms (CEChCePo CDC)
Cell polarity Epithelio-mesenchymal transition Chemotaxis Cell specification Positional transition Cell memory Differential cell adhesion Cell proliferation
Flat and thin cell extensions, serves as chemosensor; determines if a cell continues or veers away from a pathway
Lamellipodia
Longer and thinner migratory apparatus / cell extensions
Filipodia
Change in shape eg epithelial-like cells to stellate
Epithelio-Mesenchymal Transition
Directed migration of cells according to chemical gradient based on envtl cues
Chemotaxis
Promotes breakdown and release of cells from epithelium
Scatter factor
Prevents some cell migration
Chondroitin sulfate
Makes cells fat and separates them
Hyaluronic Acid
Fibrillary form which becomes the migration pathway for cells
Fibronectin
Fibronectin receptor
Integrin
Cells are already committed to what they’ll become even before migration
Cell Specification
This factor makes cell specification possible
Fibroblast Growth Factor
HOM gene complex guides cells to final location - when and where to stop
Positional Transition
Deep inside the cell, it knows its own identity; either in cytoplasm (morphogens and maternal factors) or in nucleus (genes)
Cell Memory