GASTROINTESTINAL Flashcards
GI bleed discharge score
safely from the ED
Glasgow Blatchford
Gi Bleed
Pancreatitis cause and markers
GET SMASHED
Gall Stone, Ethanol, Trauma, Steroids, Mumps, Autoimmune, Scorpian Sting, ERCP, Drugs
- Amylase + lipase
Variceal bleeds treatment
Terlopressin and Broad Spec Abx
Vomiting Blood Causes
Mallory Weis Tear Duodenal Ulcer/ Peptic Eroded ulcer Epistaxsis swallowed Varices
**Upper GI bleeding
Oesophageal
- oesophagitis
- cancer
- mallory weiss tear
- varices
Gastric
- gastric cancer
- dielafoy lesion
- diffuse erosion gastritis
- gastric ulcer
Oesophageal
Oesophagitis= small volume, usually hx of GORD
Cancer = Small volume, associated dysphagia, weightloss, recurrent
Mallory Weis tear = brisk moderate volume bright red blood following repeated vomiting. Malaena rare. Ceases spontaneously.
Varices = Large vol freshblood haemodynamically unstable
Gastric
Gastric cancer = frank hameatemesis or altered blood mixed with vomit. Erosion of major vessel = big bleed
Dieulafoy lesion = No prodromal features prior. Arteriovenous malformaiton produces considerable haemorrhage.
Diffuse erosive = Haemetemesis and epigastric discomfort. usually underlying cause e.g recent NSAID usage. Large volume haemorrhage may occur with haemodynamic comproise
Gastric ulcer: small low volume bleeds more common = fe deficient anaemia.
**Constipation
Cause
CF
IVX
drugs:
Cause: Bowel obstruction, paralytic ileus, ano-rectal stricture/fissure/prolapose, poor diet, medicaitons, hypothyroid, neuromuscular
CF: abdo pain, hair irregular stool, distension, tinkling bowel/asbent, pr bleeding
IVX: over 40 + recent change in bowel habit, PR, FBC, U+E, ca
sigmoidoscipy
Drugs: Bulk forming: fybogel Stool softener Stimulant laxative: co-danthramer or senna X in bowel obstruction Osmotic laxative: movicol- lactulose
** Diarrhoea
cause
syx
ivx
management
- drug Tx
Cause: gastroenteritis, drugs, colorectal cancer, uc/crohns, coeliac, c.diff
RF: food poisioining, travel, recent abx use
Syx: stomach cramps, V+N, anorexia, anaemia, fresh Pr bleed mucus
IvX: bloods, U+E, ESR, coeliac serology, sigmoidoscpy, stool sample, colonoscopy
Management: treat cause
ORAL rehydration
codiene phosphate or LOPERAMIDE
refer urgent if over 40+ 6 week change in bowel habit
Malnutrition
- Nutritional deficiency state of protein, energy or micronutrients causing measurable harm to body composition, function or clinical outcome
- PEM = protein-energy malnutrition
o Kwashiorkor = fair to normal energy but inadequate protein
- Oedema and hepatomegaly
o Marasmus = inadequate energy and protein= Ass with severe wasting
Oesophagitis and reflux / GORD
Cause
RF
CF:
IVX:
TX drugs:
Cause: defective sphincter, hiatus heria, increased intra abdominao pressure, h.pylori.
RF: smoking, obesity, pregnancy
CF: heartburn, retrosternal discomfort, acid brash,
IVX: FBC to exclude anaemia
Upper GI endoscopy of symtoms >4 weeks +55 yrs
Oesophageal PH monitoring
Management: lifestyle, avoid fatty spicy food and alcohol
TX: Antacids
Alginates = gaviscon
PPI lansoprazole
Ranitidine = h2 receptor agonist
Refer if > cancer eg weight loss, dysphagia
Oesophageal carcinoma
Most common?
CF:
IVX:
Management
SCC most common then adeno
RF: diet, alcohol, smokingm barrets
CF: dysphagia, vomiting, anorxia, dyspepsia
IVX: Bloods, endoscopy urget, CXR
MAnagement: abx prophylaxis and chemo/ surgery
Hiatus hernia
Sliding
Para-oesopheal
CF:
Management:
• Herniation of a part of abdominal viscera through the oesophageal aperture of the diaphragm
- Sliding (stomach moves up into oesophagus through current hole) and Para-oesophageal (out side)
RF: obesity, pregnancy, ascites
CF: Many are asymptomatic, Heart burn esp on bending or lying, GOR, Diff in swallowing
Management: Rx not needed if aymptomatic except for para-oesophageal hernias = fundoplication
PPI higher dose long term
Peptic ulcer
IVX:
Management:
- Gastric and duodenal ulcers
Gastric = worsened by eating Duodenal = relieved by eating
Cause: H.pylori, smoking, Nsaids
IVX: Upper GI endoscopy, stop PPI 2 weeks before
FE def anemia
Test for H pylori- carbon 13 urea breath test
Management: stop smoking, Triple therapy for 4 weeks
PPI + Amoxicilin + Clarithromycin / metronidazole
Gastric Carcinoma
cF:
which node associated?
ivx:
Management:
• Poor prognosis and non specific presentation
Cause: often adenocarcinoma at gastro-oesophageal junction
RF: pernicious anaemia, H.pylori, smoking
CF: dyspepsia, vomiting, decrease weight, epigastric mass, virchows node
IVX: refer- urgent 2 week wait if chronic gi bleeding/ progressive dyspepsia
FBC +LFTs + rapid access flexible endoscopy
Management: nutritional support, total/subtotal gastrectomy
Palliative chemo, corticosteroids, stenting to relieve dysphagia
Prevention: high intake fruit and veg and weight loss
Carcinoma of pancreas
95% are?
CF:
IVX:
Late presentation, early mets and poor survival rates
95% adenocarcinomas
RF: smoking, alcohol, chronic pancreatitis
CF: tumours of head pancreas can cause painless obstructive jaundice, anaemia, weight loss, acute pancreatitis, splenomegaly, diabetes
IVX: bloods, CA-19, amylase, hyperglycamiea,
USS of live and pancreas
abdo CT
Management: radical surgery- and chemo, palliation
mean survivial 6 months
Coealic disease
which HLA?
CF:
IVX:
HLA-DQ2 (90%) or HLA-DQ8 (its bad 2. 8 gluten)
Gluten - gliadin
CF: steatorrhoea, diarrhoea, abdo pain, bloating, N+V, angular stomatitis, fatigue, weakness, Fe def anaemia, weight loss, FTT, buttock wasting
IVX: ILA and HLA DQ2 testing
–> Ensure that the person has eaten gluten-containing foods in 1+ meal a day, for 6 weeks, before testing
Check serum i(Ig)A tTGA and total IgA first-line.
Endoscopy
Management: Life long gluten free diet.
Acute pancreatitis
Key clinical features?
which sign?
IVX
Management
pain relief?
Biggest cause = Gallstones and Alcohol
GETSMASHED
Gallstones, Ethanol, Trauma, Steroids, Mumps, Autoimmune, scorpian bite, hyperlipdeamia, ERCP, drugs.
CF: sudden epigrastric pain RADIATES TO BACK, vomiting, grey turner sign
IVX: Serum amylase- raised
Serum lipase = RAISED
Management: NBM, FLUIDS analgesia = pethidine
Peritonitis
- Inflammation in the peritoneum itself
- SBP = spontaneous bacterial peritonitis = occurs in pts with ascites secondary to chronic liver disease
CF: fever, pain anywhere in abdo, guarding, rigidity and lie with knees flexed
IVX: Fbc raised Acc, blood cultures, culture peritoneal fluid, urinalysis and XR
Management: Iv fluids, systemtic abx and surgery to treat cause
Inguinal hernia
• Protrusion of abdo contents through the fascia in the abdo wall, through the internal inguinal ring
RF: infants- male, obesity, constipation
CF: swelling in groin, indirect- pain in scrotum, soft and reducible
IVX: US and reduce heria and occlude deep ring
In children repair asap, adults can be left/ reduced using mesh
INDIRECT – thro’ internal inguinal ring, passes along inguinal cancal thro abdo wall – LAT to inf Epigastric vessels
DIRECT – hernia thro’ post wall inguinal canal. More common elderly. MEDIAL to inf Epigastric vessels
Femoral hernia
• Protrusion of a viscus through a defect of the walls of its containing cavity into an abnormal position
RF: mainly females
CF: lump in groin, swells during coughing. pain if incarcerated
IVX: USS,CT, MRI
Management: high risk strangulation–> elective repairment
Incisional hernia
•Failure of wound to heal
CF: Bulge or protrusion at or near area of surgical incision
Management: Bulge or protrusion at or near area of surgical incision
Umbilical hernia
E.g Congenital hernia = omphalocele or Infantile
Adult- e.g. 90% acquired in women in pregnancy
If present over 4 yrs, then repair
Gallstones + biliary colic
Fair, Fat, Fertile, Female + Forty
Biliary colic: Stones made in GB → symptomatic with cystic duct obstruction, or if passed into CBD
⇒ Sudden RUQ pain – often following food
⇒ Radiating to R.Shoulder
⇒ Persists for 15 mins
⇒ Better with analgesia
⇒ A/w nausea + vomiting
x Fever (suggests cholecystitis or cholangitis) x Jaundice (suggests cholangitis)
Cholecystitis
CF:
what sign?
IVX
Treatment:
GB becomes inflamed following stone impaction at neck of GB
CF: Constant or colicky RUQ pain (biliary colic) –> Radiates to Back or R.Shoulder
Worse when eating Fatty Foods, GB mass at RUQ (gall stone), RUQ tender
⇒ Murphy’s sign (palpate RUQ, breathe in, ↑pain)
Fever, Nausea + Vomiting, bloating, NON peritonitic ± Obstructive Jaundice (if stone moves to CBD)
NB: pain is similar to biliary colic, but much more severe
IVX: Bloods, USS abdo to visualise stone
TX:
1. Analgesia, rehydrate, NBM
2. Abx – Co-Amoxiclav
3. Laparoscopic cholecystectomy – within 1 week!!
4. Open cholecystectomy – if GB perforation
Chronic: MRCP