Gastrointestinal Flashcards

1
Q

Gingival hypertrophy which is caused by gingivectomy (bitting on own gums) is a common side a effect of which class of drugs?

A

Calcium channel blockers

Or phenytoin

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2
Q

There’s a bird beak appearance on an X-ray. What is this a sign of in the upper GI tract and what is it a sign of in the lower GI tract?

A

Upper GI tract - Achalasia
Lower GI tract - Bowel obstruction

Achalasia is a condition that affects the nerves and muscles of the oesophagus, mainly at the lower end.

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3
Q

What is grey turner’s sign?

A

Lumbar redness

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4
Q

What is Cullen’s sign?

A

Umbilical redness

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5
Q

What are grey turner’s and Cullen’s sign indicative of?

A

Acute pancreatitis

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6
Q

What is Murphy’s sign?

A

The inspiration arrest that occurs upon palpating of the right upper quadrant during a deep breath.

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7
Q

What is Murphy’s sign indicative of?

A

Cholecystitis

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8
Q

A patient comes in with the pale stools, jaundice and abdominal pain. What is the most likely diagnosis?

A

Biliary obstruction

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9
Q

A patient comes in with abdominal distension, caput Medusa’s and shifting dullness. What are his most likely diagnoses?

A

Portal hypertension

Ascites

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10
Q

A patient comes in with pyoderma gangrenosum and erythema nodosum. Which diseases are part of your differential diagnosis?

A

Ulcerative colitis and Crohn’s disease

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11
Q

A patient has tinkling bowel sounds. What is the most likely cause?

A

Bowel obstruction

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12
Q

A patient comes in with a history of weight loss and a vesicular rash. What is the likely cause of this?

A

Coeliac disease

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13
Q

What is Virchow’s node (swollen left supra-clavicular node) a sign of?

A

Gastric cancer

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14
Q

What is the urea breath test used for?

A

H pylori diagnosis

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15
Q

What is the 14C urea breath test used for?

A

To test for bacterial overgrowth (of H.pylori)

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16
Q

A patient comes in with rice water like stools. What organism is likely to be affecting this patient?

A

Vibrio cholera

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17
Q

A patient has presence of AMA (anti mitochondrial antibodies). What is this a sign of?

A

Primary biliary cirrhosis

18
Q

A patient had the presence of ASMA (anti smooth muscle antibodies). What is this a sign of?

A

Autoimmune hepatitis

19
Q

A patient’s alpha fetoprotein assay (AFP) test shows high levels of AFP. What is this likely to indicate?

A

Hepatocellular carcinoma (or teratoma)

20
Q

What is a cobblestone mucosa?

A

Deep fissuring ulceration of mucosa

21
Q

What is a cobblestone mucosa indicative of?

A

Crohn’s disease

22
Q

Which diuretic is prescribed for ascites (cause by cirrhosis)?

A

Spirolactone

23
Q

What is a corkscrew oesophagus on a barium swallow indicative of?

A

Diffuse oesophageal spasm

24
Q

A patient comes in with severe abdominal pain as well as diarrhoea and vomiting after drinking raw milk. Which organism is likely affecting him?

A

Campylobacter

25
Q

What is Russell’s sign indicative of?

A

Self induced vomiting

26
Q

What are Mallory’s hyaline bodies indicative of?

A

Alcoholic liver disease (acute hepatitis)
or
Chronic active hepatitis

27
Q

What are crypt abscesses a sign of?

A

IBS or Crohn’s disease

28
Q

A patient’s pathology report shows onion skinning fibrosis and heading of the bile duct. What is the most likely diagnosis?

A

Primary sclerosing cholangitis

29
Q

Signet ring cells are seen on a biopsy. What is this a sign of?

A

Diffuse stomach cancer

30
Q

There’s thumb printing on an X-ray at the splenic flexure. What is this indicative of?

A

Ischemic colitis

31
Q

What is Charcot’s triad?

A

Fever, jaundice and abdominal pain secondary to cholelithiasis

32
Q

What is Charcot’s triad a sign of?

A

Acute cholangitis

33
Q

What are some causes of an abdominal mass?

A

A - Abdominal aortic aneurysm

C - Crohn’s disease 
H - Hernia
E - Enlarged organ
M - Malignancy
I - Intersusception
C - Cyst or abscess
A - Appendicitis
L - Lymphadenopathy
34
Q

What are some causes for bowel obstruction?

A

B - Bolus
A - Adhesions
T - Tumour
H - Hernia

V - Volvulus
I - Intersusception
P - Pseudo obstruction
S - Stricture

35
Q

What is the side effect of spironolactone?

A

Gynaecomastia

36
Q

What is a common oral disease in people with Crohn’s?

A

Stomatitis gangrenosum

37
Q

What is Barrett’s oesophagus characterized by?

A

Replacement of oesophageal stratified epithelium by simple columnar epithelium with goblet cells

38
Q

What are the three stages of Dukes classification?

A

A - Confined to the bowel wall
B - Local spread outwith the bowel wall
C - Lymph node metastases

39
Q

What are some causes of liver disease?

A
A - Autoimmune
B - Hepatitis B
C - Hepatitis C
D - Drugs such as paracetamol
E - Ethanol 
F - Fatty liver disease
G - Growth
H - Haemodynamic e.g. congestive heart failure
I - Infiltration e.g. haemochromatosis or Infective
40
Q

How can you remember that AST levels increase in alcoholic liver disease?

41
Q

What are some causes of abdominal distension?

A
Fat
Firth’s
Flatus
Faeces
Fluid
Fucking massive tumour