Gastrointestinal Flashcards
What is the mechanism of action of Gaviscon?
When would you prescribe it?
Gaviscon inhibits the proteolytic pepsin enzyme which neutralises stomach acid
It is prescribed to treat heartburn and indigestion
What is the mechanism of action of Loperamide?
When would you prescribe it?
Loperamide binds to the opiate receptor in the gut wall and slows the passage of food through the gut
Loperamide is used to treat sudden or recurrent diarrhoea
What is the mechanism of action of Lansoprazole?
When would you prescribe it?
Lansoprazole is a proton pump inhibitor that inhibits gastric hydrogen/potassium adenosine triphosphatase, blocking the secretion of gastric acids
Lansoprazole is used to treat gastro-oesophageal reflux and can also be used for peptic ulcers
What is the mechanism of action of Omeprazole?
When would you prescribe it?
Omeprazole is a proton pump inhibitor that irreversibly inhibits the hydrogen/potassium adenosine triphosphatase, inhibiting the secretion of gastric acid
Omeprazole is used to treat stomach/duodenal ulcers and reflux oesophagitis
What is the mechanism of action of Ranitidine?
When would you prescribe it?
Ranitidine reversibly binds to histamine receptors, which reduces the secretion of gastric acid
Ranitidine is used to help stomach ulcers to heal
What drug classification does the components of Gaviscon belong to?
Antacids
What drug classification does Loperamide belong to?
Antidiarrhoeal - opioid receptor agonists
What drug classification does Lansoprazole and Omeprazole belong to?
Proton Pump Inhibitors
What drug classification does Ranitidine belong to?
Histamine H2 Antagonist
