gastroenterology Flashcards

1
Q

What type of cell provides a protective barrier against damage from mechanical trauma from peristalsis, autodigestion and acid. and how?

A

Mucous neck cells
Producing bicarbonate and mucous

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2
Q

What cells stimulates gastric acid secretion by the parietal cells? and how?

A

Enterochromaffin-like cells
Produce histamine

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3
Q

What cells inhibit gastric secretion and how?

A

D cells.
They secrete somatostatin
(hypothalamus also secretes this)

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4
Q

What cells are responsible for the digestion of protein into amonio acids? How?

A

Chief cells
They secrete pepsinogen which is converted to pepsin

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5
Q

What cells are responsible for producing gastric acid? and what is the bonus thing they secrete?

A

Parietal cells
hydrochloric acid converts pepsinogen into pepsin
Intrinsic factor.

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6
Q

Where are G cells located? what do they secrete?

A

Pyloric area.
Gastrin - is integral in stimulation of the parietal and chief cells to produce their enzymes.

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7
Q

Where is Ghrelin produced and what does it do?

A

Fundus of the stomach.
Stimulates appetite and growth hormone secretion

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8
Q

Where is Leptin secreted and what does it do?

A

adipocytes
suppresses hunger

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9
Q

What cells neutralise hydrochloric acid in the stomach?

A

Acinar cells of the pancreas
proenzymes trypsinogen, chymotrypsinogen and procarboxypeptidase and also sodium bicarbonate

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