Gastro - part 1 Flashcards
What is dumping syndrome?
Rapid emptying of hypertonic chyme from the surgically residual stomach
What is a simple instetinal obstruction?
it is a mechanical blockage via lesion (most common)
- luminal obstruction without impairment of blood supply
What is small volume diarrhea caused by?
o Ulcerative colitis
o Chron’s disease
o Microscopic colitis
o Colon cancer
o Fecal impaction
What symptoms contribute to acid reflex?
Vomiting coughing, lifting bending, obesity, or pregnancy increases abdominal pressure, contributing to reflux
Signs and symptoms of appendicitis?
initially – vague epigastric pain, cramping sensation
Over 24 hours – pain becomes more localized in RLQ
Will also see anorexia, nausea or vomiting, low-grade fever, rebound tenderness on palpation
Following rupture – brief cessation of pain – untreated it is fatal
What is secretory diarrhea caused by?
Produces large-volume diarrhea caused by:
o Viruses (ie. Rotavirus)
o Bacterial enterotoxins (ie E coli and V coli)
o Exotoxins from C difficile
o Small bowel bacterial overgrowth
What is secondary constipation caused by?
Diet, medication, or neurological disorders in which neural pathways or neurotransmitters are altered and colon transit is delayed
What symptoms accompany chronic diarrhea that’s caused by inflammatory bowel disease or dysentery?
- Fever
- Cramps
- Bloody stool
- Steatorrhea (fat in stools)
- Bloating
Risk factors for GERD?
Risk factors – age, obesity, hiatal hernia (stomach bulges up into your chest through an opening in diaphragm), medications that relax the lower esophageal sphincter
What are we going to have with exposure to stomach acid in acid reflex?
Metaplasia due to changing cells from exposure to stomach acid
What is Emesis?
forceful emptying of stomach and intestinal contents
Caused by extreme pain, stomach or duodenum distension, motion sickness, side effects of medications, trauma
Usually preceded by nausea – retching
What is slow - transit constipation?
It involves impaired colonic motor activity with infrequent bowel movements, staring to deficated, mild abdominal distention, and palpable stool in the sigmoid colon
With GERD what may be a precursor to cancer in the esophagus?
stomach acid changes the lining of the esophagus – may be precursor to cancer of esophagus
What is intussusception? what population is it more common in?
Telescoping one part of the intestine into another (this usually causes strangulation of blood supply)
*More common in infant 10-15mon of age rather than adults
What is paralytic ileum?
(Functional GI obstruction)
failure of intentional motility that is often occurring after intestinal or abdominal surgery, acute pancreatitis, or hypokalemia
Signs and Symptoms for acute gastritis?
vague abdominal discomfort epigastric tenderness, & bleeding
What is GERD?
- More serious form of acid reflex (chronic acid reflex)
What is appendicitis? What happens if it ruptures?
Inflammation of the appendix
If it ruptures you have stool going into tour perineum
What is hematochezia?
bright red stools, but generally some digested blood components would have occurred producing melena
What is Ulcerative Colitis? where do we see it?
It is a chronic inflammatory disease that causes ulceration of the colonic mucosa, most commonly in the rectum and sigmoid colon
- Ulcerations of the mucosa in the colon
What is secretory diarrhea?
Excessive muscosa secretion of fluid and electrolytes produces large volume diarrhea
What is anorexia associated with?
o Associated with nausea, abdominal pain, diarrhea, and psychological stress
What are the structures of lower GI bleeds?
jejunum, ileum, colon, rectum
What is Nonimmune (astral) gastritis caused by?
H.pylori, and is associated with the use of alcohol, tobacco, and NSAIDs
How is Diarrhea classified?
More then 14 days to 4 weeks = persistent
more then 3 loose stools within 24 hours lasting less than 14 days
How are upper GI tract bleeds characterized?
frank, bright red bleeding or dark grainy digested blood that has been affected by stomach acids
What is Steatorrhea?
Fat in stool
What are the systematic effects of prolonged diarrhea?
Dehydration
Electrolyte imbalance (hyponatrmia, hypokalemia)
Weight loss
What is functional constipation associated with?
o Sedentary lifestyle
o Highly refined foods
o Low fluid intake
What is visceral abdominal pain?
It arises from the stimulus acting on an organ (distension and inflammation)
- Poorly localized, diffuse or radiating
What does Chronic immune (fundal) gastritis lead to?
The gastric mucosa degenerates extensively in the body and fungus of the stomach, leading to gastric atrophy
leads to gastric atrophy, which diminishes acid and intrinsic factor, causing pernicious anemia (lack of Vit B12 absorption)
Complications of a duodenal ulcer?
What is the most common cause of mortality, particularly among older persons with a duodenal ulcer?
Complications include bleeding, perforation, and obstruction of the duodenum or outlet of the stomach
- most common cause of mortally amount older persons is bleeding
what do gastric ulcers cause more of compared to duodenal ulcers?
They cause more anorexia, vomiting, and weight loss than duodenal ulcers
What are predisposing factors to diverticulosis?
older age, genetic predisposition, obesity, smoking, diet, sedentary lifestyle, & meds such as aspirin and NSAIDS
What is parietal (somatic) abdominal pain? Where does it arise from?
It arises from the parietal peritoneum
**Localized and intense
- Arises from the organs themselves
- Pain lateralizes
What can steatorrhea indicate?
Alterations in liver and pancreatic functions
What is a Cushing’s ulcer? Where are they commonly located?
Stress ulcer that is associated with with severe brain trauma or brain surgery
Most common site os the stomach
What is functional constipation?
Involves normal rate of of still passage, but there is difficulty with stool evacuation
What is Gastritis?
It is an inflammatory disorder of the gastric mucosa
What are some complications of diverticulitis?
abscess, fistula, obstruction, bleeding, or perforation
What is alkaline reflux gastritis? Signs and symptoms?
-inflammation caused by reflux of bile and alkene pancreatic secretions
nausea, vomiting bile, epigastric pain
What is diverticulitis associated with? how is it idiopathic?
It is associated with increased intracolonic pressure, abnormal neuromuscular function, and alterations in intestinal motility
Idiopathic – related to increased intracolonic pressure, abnormal neuromuscular function, and alterations in intestinal motility
What are the 5 indicators of constipation? How long do you need to have them for?
You need to have at least 2 of these indicators for 3 months
1.) Straining with defecation 25% of the time
2.) Lumpy or hard stools 25% of the time
3.) Sensation of incomplete emptying 25% of the time
4.) Manual manoeuvres to facilitate evacuation 25% of the time
5.) Fewer than 3 bowel movements per week
What is Chronic immune (funal) gastritis? What is it associated with? what does it lead to?
Rarest from of gastritis and is associated with the loss of T cells tolerance and development of autoantibodies to gastric H+ -K+ ATPase.