Gastro #1 Flashcards
dysphagia vs odynophagia
dysphagia- difficulty swallowing
odynophagia- painful swallowing (indicates inf process)
most common diagnostic modalities for esophageal disroders
barium swallowing (esophagram)
esophagogastroudodenoscopy (EGD/OGD)
Esophageal manometry
24h pH monitoring
GERD facts + what is it due to
1st identifiable cause for epigastric pain (10-20% of people in the West)
due to excessive relaxation of lower esophageal sphincter (LES)
risk factors for GERD
obesity, old age, hiatus hernia, family hx, meds (Ca2+ channel blockers)
investigations for GERD if chest pain? (4)
- EKG to exclude heart
- Clinical dx using proton pump inhibitors
- gastroscopy
- espphageal manometry
S&S of GERD
heart burn, chest pain, dysphagia, odynophagia
chest pain, chronic cough, wheezes (THIS COULD BE HEART CONDITION)
GERD treatment
proton pump inhibitors (PPIs), H2-antaognists
avoid certain foods and weight loss (and raise head in bed)
Big complication from GERD
Barrett’s esophagus + esophageal adenocarcinoma
can also have esophagitis, ulcer, bleeding, esophageal stricutre disease
what is barrels epophagus and what is it due to
Metaplasia of normal squamous esophageal epithelium to abnormal columnar epithelium
Due to long standing GERD
what does barrett’s esophagus predispose to?
adenocarcinoma
Esophageal Motor Disroders (3)
- Achalasia
- Scleroderma
- Diffuse Esophageal spasm
What is Achalasia and what is it due to
Failure of smooth muscle relaxation at LES (incomplete relaxation of the lower esophageal sphincter)
increased LES pressure
progressive loss of peristaltic function
due to malignancy, idiopathic or chagas disease
investigations for achalasia and best test (4)
Chest x ray Barium studies (birds beak at end of esophagus)- best initial test endoscopy manometry- most accurate test
most accurate test for scleroderma
manometry
Tx for scleroderma
Agressive GERD therapy with PPIs