Gastritis Flashcards
How many types of gastritis exist?
Acute vs Chronic
What are the clinical symptoms of acute gastritis?
- gastric erosions (mucosa only)
- epigastric pain
- melena (rare)
- nausea/vomiting
Which cells are elevated in acute and chronic gastritis respectively?
Acute gastritis: neutrophil elevation
Chronic gastritis: lymphocytes and plasma cells
What are the two types of chronic gastritis?
- Autoimmune gastritis (type A)
2. Helicobacter pylori gastritis
What is a risk factor of chronic gastritis?
Gastric adenocarcinoma
Which antibodies are diagnostic of chronic gastritis?
- ANTI-PARIETAL CELL ANTIBODIES
- ANTI-IF ANTIBODIES
What investigation would you undertake if H.pylori is suspected?
- Stool antigen test
- Urease breath test
- Serology
What is the preferred treatment for H.pylori gastritis?
Antacids and antibiotics
In chronic autoimmune gastritis, the autoantibodies are directed towards?
Parietal cells and intrinsic factor B12.
Which part of the epithelium is affected in acute gastritis?
Only mucosa layer.
In chronic gastritis type B (H.pylori infection), which part of the stomach is affected?
Antrum of the stomach
What are the two types of gastric ulcers in acute gastritis?
- Curling’s ulcers
2. Cushing’s ulcers
What is the most important histological finding for Menetrier disease?
Hypertrophic gastric rugae and parietal cell atrophy
In autoimmune chronic gastritis, the gastrin level and the gastric acid are respectively?
gastrin is high
gastric acid is low
Chronic gastritis presents with decreased serum levels of?
PEPSINOGEN
