Gastric Cancer Flashcards
1
Q
How many types of gastric cancer exist?
A
- Intestinal (well differentiated)
2. Diffuse (undifferentiated)
2
Q
What is the difference of intestinal gastric cancer with diffuse gastric cancer?
A
In intestinal gastric cancer, only the lesser curvature of the stomach is affected whereas diffuse gastric cancer affects any part of the stomach.
3
Q
What are the causes of intestinal gastric cancer?
A
- H. Pylori
- Smoking
- Chronic gastritis
- Smoked foods
- Low gastric acid
4
Q
What is the mutation associated with diffuse gastric cancer?
A
It is a mutation of CDH1 gene encoding for E cadherin
5
Q
Name a histological complication of the stomach in diffuse gastric cancer.
A
Linitis plastica
