Gastric Cancer Flashcards
The majority of gastric cancers are what
Adenocarcinoma (90%)
What are intestinal gastric cancers, and what % of cancers do they make up in the stomach
80%
- Well differentiated tubular and glandular formations
What are diffuse gastric cancers
Poorly differentiated tumours which diffusely infiltrate the stomach wall- poor prognosis
What are the risk factors for gastric cancer
- H. Pylori
- Male
- Increased age
- Diet and lifestyle
Symptoms of gastric cancer (5)
- Weight loss (present in 60%)
- Epigastric pain is a late sign
- Nausea and anorexia
- Vomiting, dyspepsia and dysphagia
- Upper GI bleeding
- Symptoms of anaemia
Signs of gastric cancer (4)
- Epigastric mass
- Hepatomegaly/ jaundice/ ascites
- Virchow’s node
- Acanthosis nIGRICANS
What investigations are used to make a diagnosis of gastric cancer
Gastroscopy and biopsy
What is the curative surgery used for gastric cancer
Total gastrectomy and lymphadenectomy
What is the palliative surgery used for gastric cancer
Subtotal gastrectomy
5 year survival?
15%
What medical treatment for gastric cancer is there
Chemotherapy
- perioperative chemo
- Trastuzumab is HER2+
