Gas Exchange in Humans Flashcards

1
Q

What is the organ of gaseous exchange in humans (and other mammals)?

A

The lungs

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2
Q

Why is it important for the lungs to be efficient?

A

To allow mammals to be very active animals

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3
Q

What are the main components of the human gas exchange system?

A

Trachea, bronchi, bronchioles, alveoli

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4
Q

What is the alveoli?

A

The site of gaseous exchange

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5
Q

What are the trachea and bronchi held open by, why is this beneficial?

A

They are held open by bands of cartilage to prevent them from collapsing and to ensure constant air flow

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6
Q

What is the wall of an alveolus made up of?

A

A single layer of squamous epithelium

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7
Q

What is an advantage of squamous epithelial cells being very thin?

A

They are freely permeable to respiratory gases

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8
Q

How many cells this are the blood capillaries surrounding the alveoli?

A

One cell thick

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9
Q

Where does oxygen dissolve on the epithelium and where does it diffuse into?

A

Oxygen dissolves in the film of water on the surface of the epithelium and diffuses across into the blood capillary

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10
Q

What do the alveolar epithelium secrete?

A

A phospholipid surfactant

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11
Q

What is the role of the phospholipid surfactant secreted by the alveolar epithelium?

A

They decrease surface tension and so prevent alveoli from collapsing as they recoil after each breath

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12
Q

What is ventilation?

A

The exchange of air in the lungs with ambient air.

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13
Q

What does ventilation ensure?

A

A steep diffusion gradient is maintained across the alveoli

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14
Q

How is ventilation achieved?

A

By changes in the volume of the thoratic cavity and associated changes in pressure in the lungs

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15
Q

What happens to the external intercostal muscles in inspiration?

A

They contract

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16
Q

What happens to the internal intercostal muscles in inspiration?

A

They relax

17
Q

How does the rib cage move in inspiration?

A

The rib cage moves up and out

18
Q

What happens to the diaphragm muscle in inspiration?

A

It contracts and moves down

19
Q

What happens to the volume of the thoratic cavity in inspiration?

A

It increases

20
Q

What happens to pressure in the lungs in inspiration?

A

Pressure in the lungs decreases and becomes lower than atmospheric pressure

21
Q

What happens to air flow in inspiration?

A

Air flows into the lungs down a pressure gradient

22
Q

Describe the process of inspiration

A

External intercostal muscles contract
Internal intercostal muscles relax
Rib cage moves up and out
Diaphragm muscle contracts and moves down
Volume of thoratic cavity increases
Pressure in the lungs decreases and becomes lower than atmospheric pressure
Air flows into the lungs down a pressure gradient

23
Q

What happens to the external intercostal muscles in expiration?

A

They relax

24
Q

What happens to the internal intercostal muscles in expiration?

A

They contract

25
Q

How does the rib cage move in expiration?

A

It moves down and inwards

26
Q

What happens to the diaphragm muscle in expiration?

A

Relaxes and moves up

27
Q

What happens to the volume of the thoratic cavity in expiration?

A

It decreases

28
Q

What happens to pressure in the lungs in expiration?

A

Pressure in the lungs increases and becomes higher than atmospheric pressure

29
Q

What happens to air flow in expiration?

A

Air flows out of the lungs down a pressure gradient

30
Q

Describe the process of expiration

A

External intercostal muscles relax
Internal intercostal muscles contract
Rib cage moves down and inwards
Diaphragm muscle relaxes and moves up
Volume of thoratic cavity decreases
Pressure in lungs increases and becomes higher than atmospheric pressure
Air flows out of the lungs down a pressure gradient