gaos objectivs

Question 1

nomenclature electic

Answer 1

common in astocytes and in development and inhibitory interneurons
called electircal/electrotonic signaling/coupling
gap junctions

Question 2

structure/comp electric

Answer 2

gap junction of with connexin on either membrane, usually clustering
no pre/post difference

Question 3

sturcutre/comp chem

Answer 3

pre vs post differences
Type I - asymmetric, on dendrites for EPSP
Type II - symettricon cell body for IPSP

Question 4

fucntion of electric

Answer 4

super fast, bi directional, dont care much for threshold
low pass filter, frequency dependent 
PSPs are more stable
SYNCHRONY SYNCHRONY SYNCHRONY
important for IPSP

Question 5

func of chem

Answer 5

IPSP or EPSP to or not to AP

temporal and spatial summation

Question 6

gap junctions

Answer 6

large clusterd groips of connexin channels

Question 7

connexin

Answer 7

protien of channel for gap junctions
Cx43 for astrocytes
Cx36 for neurons 
in vetebrates only
pannexin is in both

Question 8

proof of chemical

Answer 8

hyperpolarization

Question 9

connexin knockout

Answer 9

loss of fine motor control

Question 10

steps of chemical transmission

Answer 10

pre depolarie
ca in
vessicles relase NT
Nt in cleft
NT bind post rec
IPSP or EPSP

Question 11

life cycle of NTs

Answer 11

Precursers come into pre
syntheis with enzymes and cofactos
stored in vessicles
release/exocytosis cuz Ca
Activation - binding receptors
termination - diffuse back in, enzymatic degreade in cleft, or reuptake by proteins or autoreceptors

Question 12

quanta release

Answer 12

amount of NT in a vesicle

Question 13

EPSP vs IPSP

Answer 13

EPSP toward threshold, decreases membrane potential?

IPSP hyperpolarize increases? weird