Ganglionic agents Flashcards
1
Q
Define Nicotine
A
Nicotine is a stimulant and Inhibitor.
2
Q
Mecamylamine
A
Mecamylamine is a Ganglionic inhibitor
3
Q
How is Nicotine Unique?
A
Nicotine is a Nicotinic Receptor agonist at low doses.
Nicotine is a Nicotinic Receptor antagonist at high doses.
4
Q
What are the important sites of nicotine action?
A
Affects all Nicotinic receptor subtypes in CNS Cardiovascular and GI, Skeletal Muscle.
5
Q
Know the table on slide 5
A
Know the table on slide 5
6
Q
What are key symptoms of Nicotine Poisoning?
A
GI- nausea vomiting diarrhea
Heart- Hypotensive Fainting
CNS- respiratory paralysis
7
Q
What is the fatal dose of nicotine?
A
60mg
8
Q
Nicotine for smoking sedation
A
Gum, patches, sprays , inhalers
