Gametogenisis Flashcards

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1
Q

what is gametogensis

A

the process where specialsied cells, or gametes are produced. occurs in the gonads, for sexual reproduction.

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2
Q

gemetogensis in females

A

oogenesis

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2
Q

what are gonads

A

glands that produce hormones involved in reproduction.
testes - in males
ovaries - in females.

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3
Q

gemetogensis in males

A

Spermatogenesis

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4
Q

components of the testes

A

includes the twisted and coiled - seminiferous tubules, where sperm is made and the epididymis, where the sperm further matures (longer flagella and more mitochondria), and get ready for ejaculation.

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5
Q

what are the components of the seminiferous tubules

A

has a smooth muscle layer - to help propel the sperm from the tubules into the epididymis.
and many sertoli cells,

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6
Q

what is the process, of movements of the sperm from tubules into the epididymis.

like squeezing toothpaste from bottle.

A

peristalis. l=wave like muscle contraction.

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7
Q

where is the sperm made in the seminiferous tubules

A

in between 2 sertoli cells.

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8
Q

what is the precursor of the sperm cell, or the intial cell where all the sperm comes from.

A

the Spermatogonium, they are the undifferentiated germ cells in the testes.

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9
Q

where is the tight junction found, and what is its function

A

found near the far ends of the sertoli cells, which seperates the basal compartment (outside area of the tubules) and the lumenal compartments.
- it opens up to let the primary spermocytes through, and closes up immediately, to prevent leakege and maintain optimum environments.

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10
Q

what is the primary spermocyte formed from, and how.
how many chromoseoms does it have.

A

formed from the intial spermatogonium. formed by mitosis and then differentiation.

A diploid cell with 46 chromosomes.

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11
Q

what 2 cells does the mitosis of spermatogonium, result in.

A

1 cell undergoes differentiation, to form the priamry spermatocyte, and the other cell essentially reverts back to reform another spermatogonium.

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12
Q

the (diploid) primary spermocyte’s cytoplasm grows in size, what happens after.

A

the primary spermocyte undergoes corssing over in prophase 1, and then
dividies into 2 secondary spermocytes, by meiosis 1.
now the secondary spermocytes are haploid cells with 23 chromosomes, still with 2 sister chromatids.

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13
Q

what do the secondary spermocytes divide into,
how many chromosomes, do the products have

A

each secondary spermocytes, divides into 2 spermatids each, during meiosis 2. here the sister chromatids have seperated.
results in each spermatid being a haploid - having 23 chromosomes, and one sister chromatid each.

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14
Q

How is the spermatozoa formed.

A

spermatids are differentiated into spermatozoa, through the process of speriogenesis.

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15
Q

where does further maturation (spermoiogenesis) of the formed spermatozoa occur and what is included.

A

At the border of them lumen,

  • the removal of excess cytoplasm and organelles including ribosomes and endoplasmic reticulum.
  • Forming a streamlined, motile cell
  • further condensation of chromatin.
  • acrosome matures from the golgi complex, acrosin enzymes and other polysaccharides.

all allowing them to become functional cells.

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16
Q

how long does maturation of the spermatozoa take

A

usually 2-3 weeks.

17
Q

how many spermatozoa are formed by a single diploid spermatogonium

A

4

18
Q

when does spermatogenesis occur in males

A

at around ages 10-14, when puberty starts

19
Q

describe a timeline of how spermatogenesis starts from fetal developments until puberty.

A

fetal development = spermatogenia under mitosis, increasing in number.

start of puberty (10-14 years) - meiosis starts.
- under the influence of hormonal changes, differentiation occurs and other processes result in spermatozoa forming.

20
Q

what does the head of a sperm cell consist of

A

the nucleus, cell membrane and acrosome cap.

21
Q

describe the acrosome cap -
- how it is formed
- structure
- function

A

made from the goli complex during spermiogenesis.
consists of the acrosin enzyme, and other polysaccharides.
- has its own acrosomal membrane.
- involved in the recognition of te oocyte based on it’smolecule composition = chemotaxis,

22
Q

describe the midpiece -
main characterisitic of it.

A

contains tightly packed mitochondira = energy for swimming and apoptosis.

23
Q

where is the centriole found in a sperm cell.

main function?

A

between the head and the midpiece, refrerred to as the centrole-centrosome complex.

essential for movement, and production of mitotic apparatus for seperating chromsomes, whilst being a template for all subsequent centrioles.

24
Q

what % does the tail make up of the sperm cell

A

about 80%

25
Q

what is the main germ cell that starts oogenesis

A

the oogenium

26
Q

what happens to the oogonium first, in oogenesis

A

it undergoes mitosis, increasing no. of cells, forming the primary oocyte. (upto 1-2 mill).

27
Q

what cell division phase are primary oocytes arrested in

A

prophase 1.

28
Q

where does the mitosis of the ooogonium to form primary oocyte occur

A

in the utero - before birth. (the womb).

29
Q

when does the primary oocyte leave the prophase 1 arrest, and what happens after.

A

leaves after puberty, undergoes meiosis 1, to form the secondary oocyte with 23 chromosomes (1n) and the 1st polar body.

30
Q

how are polar bodies formed and what are they

A

they are formed, by unequal division of a cell, the (primary and secondary) oocyte being the larger and more important of the two. the polar body has less of the cytoplasm, but equal chromosomal content.
- later dies.

31
Q

what meiotic phase is the secondary oocyte arrested at

A

metaphase 2.

32
Q

what triggers the meiotic division of the primary oocyte into the secondary oocyte.

A

at adolescence, the aterior pituirty hormones cause the development of many follicles in the ovary. which finishes the first meiotic division = secondary oocyte

33
Q

what happens to the seoncdary oocyte during ovulation, (if no sperm enters)

A

the secondary oocyte travels through the fallopian tubes, on its way to the uterus, without every finishing meiosis 2.
- gets disingrated there and later any remaining material will be shed from the body in the next period.

34
Q

where does the sperm meet the egg cell. for fertilisation to occur.

A

the sperm travels from the uterus into the fallopian tubes where fertilisation with the ovum occurs.

35
Q

when is the egg oficially called the ovum in oogenesis

A

called the ovum, only after the egg has been fertilised.

36
Q

what processes happen for the second oocyte to become the ovum, and another polar body.

A

meiosis 2 continues and obvs fertilisation.

37
Q

what does the genetic makeup of the fertilised egg consist of

A

a diploid cell with -
23 chromosomes from the father and 23 chromosomes from the mother.

38
Q

what happens during ovulation

A

the secondary oocyte is released into the uterus (still in metaphase 2) through the oviduct.

39
Q

in what process does the sperm and egg cell nuclei fuse

A

during syngamy, which occurs after the sperm penetrates the egg, during fertilisation.

40
Q

when does ovum become a zygote

A

after fertilisation

41
Q

what is the difference in terms of of number of gametes produced during oogeneis and spermatogenesis

A

spermatogenesis = 4 functional sperm cells from 1 speratogonium

oogenesis = 1 egg and 2 polar bodies from each oocyte.