Gametogenesis Flashcards
Which of the following is responsible for most cases of male infetility?
A. Cystic fibrosis mutation(s)
B. Inversions
C. Klinefelter (46,XXY)
D. Microdeletions of the Y chromosome
E. Translocations
E. Translocations
Donor eggs would be an appropriate therapy for all of the following disorder except
A. Female infertility past the age of 43
B. Gonadal dysgenesis
C. Poor egg quality after repaeated IVF attempts
D. Presence of DAZ gene
E. Turner syndrome
D. Presence of DAZ gene
I think this has to do with azospermia or something similar. It’s not in the syllabus
What tissue would be best to sample for pre-implantation genetic diagnosis of Hemophilia A?
A. Blastomere biopsy from a 4 cell embryo
B. Blastomere biopsy from an 8 cell embryo
C. Polary body biopsy
D. Sperm
E. Trophectoderm biopsy (CVS)
B. Blastomere biopsy from an 8 cell embryo
In oogenesis, meiosis 1 is completed at:
A. birth
B. fetilization
C. implementation
D. ovulation
E. puberty
D. ovulation
In oogenesis, the mitotic divisions that precede meiosis are completed in utero. As a result the germ cell population
does not ever expand beyond the number present at birth. Although meiosis I starts during fetal development, it
arrests before birth and won’t resume until ovulation many years (decades) later
Flow cytometry for gender selection would best be used on:
A. Amniotic fluid
B. Eggs
C. Embryos
D. Sperm
E. Villous trophoblasts (placental cells)
D. Sperm
At the present time pre-implantation genetic diagnosis (PGD) is unable to determine the:
A. complete karyotype of 23 chromosome pairs
B. gender of an embryo
C. presence of a Robertsonian translocation
D. presence of a single gene defects
E. presence of trisomy 21
A. complete karyotype of 23 chromosome pairs
Which is most appropriate testing options for about 6 weeks in to pregnancy tot est for trisomy 21?
A. 9 weeks with CVS
B. 10 weeks with amnio
C. 10 weeks with CVS
D. 15 weeks with CVS
E. 24 weeks with amnio
C. 10 weeks with CVS
