Gallstones Flashcards

1
Q

Risk factors for gallstones

A

Female, age, obesity, rapid weight loss, multiparity, high cholesterol, oral contraceptive, ileal disease

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2
Q

Symptoms of gallstones

A

Asymptomatic
Biliary colic - sharp intermittent epigastric/RUQ pain. Worse after eating, resolves over 30-90mins.
Associated nausea and vomiting, indigestion, flatulence

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3
Q

Signs of gallstones

A

Jaundice

Poorly localised pain (no murphys sign)

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4
Q

Investigations of gallstones

A

Ultrasound scan

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5
Q

Management of gallstones

A

Cholecystectomy
Ursodeoxycholic acid treatment - reduces cholesterol saturation of bile
Dietary changes - reduce intake of fat and acidic foods to reduce incidence of biliary colic

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6
Q

Complications of gallstones

A
Cholecystitis 
Mucocoele (distension of gallbladder)
Ascending cholangitis 
Acute pancreatitis 
Gallbladder perforation
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7
Q

Pathophysiology of gallstones

A
Bile salts (cholesterol, calcium and bile pigment) precipitate out of solution in gallbladder to form hard stones
Block the cystic duct when gallbladder contracts
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8
Q

Gallstones differential diagnosis

A
Peptic ulcer disease
Pancreatitis 
GORD 
IBS
Cancer of gallbladder  
Hepatitis
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