GABA B RECEPTORS Flashcards
What is the primary function of GABA B receptors?
GABA B receptors primarily function as inhibitory neurotransmitter receptors in the central nervous system.
True or False: GABA B receptors are ionotropic receptors.
False: GABA B receptors are metabotropic receptors.
Which class of drugs is known to act on GABA B receptors?
Baclofen is a drug that acts on GABA B receptors.
Fill in the blank: GABA B receptors are involved in the modulation of __________.
neurotransmitter release.
Multiple choice: Which of the following drugs is a GABA B receptor agonist? A) Diazepam B) Baclofen C) Phenobarbital
B) Baclofen
What type of signaling do GABA B receptors utilize?
GABA B receptors utilize G-protein coupled signaling.
True or False: GABA B receptors can lead to hyperpolarization of the neuron.
True
What effect does baclofen have on spasticity?
Baclofen reduces spasticity.
Fill in the blank: GABA B receptors are primarily located in the __________ and __________.
brain; spinal cord.
Multiple choice: Which of the following conditions is baclofen used to treat? A) Anxiety B) Epilepsy C) Muscle spasticity
C) Muscle spasticity
What is the mechanism of action of GABA B receptor agonists?
They activate GABA B receptors, leading to decreased neuronal excitability.
True or False: GABA B receptors are involved in the process of long-term potentiation.
False: GABA B receptors are primarily involved in inhibition.
What is the role of GABA in the central nervous system?
GABA serves as the main inhibitory neurotransmitter in the CNS.
Multiple choice: Which of these is NOT a characteristic of GABA B receptors? A) Metabotropic B) Ionotropic C) G-protein coupled
B) Ionotropic
Fill in the blank: The activation of GABA B receptors can lead to the opening of __________ channels.
potassium
What type of drug is commonly used for alcohol withdrawal symptoms that acts on GABA B receptors?
Baclofen
True or False: GABA B receptors can form heteromers with other receptor types.
True
What is the clinical significance of GABA B receptor antagonists?
They may have potential therapeutic uses in treating certain disorders.
Multiple choice: Which of the following is a side effect of baclofen? A) Increased anxiety B) Sedation C) Insomnia
B) Sedation
What is the relationship between GABA B receptors and pain modulation?
GABA B receptors play a role in the modulation of pain pathways.
