CB1 DRUG RECEPTOR Flashcards
What are CB1 receptors primarily associated with?
The endocannabinoid system.
True or False: CB1 receptors are found primarily in the peripheral nervous system.
False.
Name one class of drugs that interact with CB1 receptors.
Cannabinoids.
Fill in the blank: CB1 receptors are a type of __________ receptor.
G-protein coupled.
What is the primary endogenous ligand for CB1 receptors?
Anandamide.
Which class of drugs is known to be an antagonist at CB1 receptors?
Rimonabant.
True or False: Activation of CB1 receptors is associated with increased appetite.
True.
Multiple Choice: Which of the following is NOT a function of CB1 receptor activation? A) Pain relief B) Increased anxiety C) Appetite stimulation D) Memory impairment
B) Increased anxiety.
Short answer: What is one potential therapeutic application of CB1 receptor agonists?
Management of chronic pain.
Fill in the blank: CB1 receptors are primarily located in the __________.
Brain.
What effect do CB1 receptor agonists typically have on mood?
They can induce euphoria.
True or False: Cannabidiol (CBD) primarily acts on CB1 receptors.
False.
Multiple Choice: Which cannabinoid is known for its psychoactive effects through CB1 receptor activation? A) CBD B) THC C) CBG D) CBN
B) THC.
What is the role of CB1 receptors in the central nervous system?
They modulate neurotransmitter release.
Short answer: What is the primary effect of CB1 receptor antagonism?
Reduction of appetite.
Fill in the blank: The __________ system is crucial for the pharmacological effects of cannabinoids.
Endocannabinoid.
True or False: CB1 receptors are involved in the regulation of memory.
True.
Multiple Choice: Which of the following is a characteristic of CB1 receptors? A) They are exclusively found in the lungs B) They are a type of ion channel C) They are widely distributed in the brain D) They are only active during inflammation
C) They are widely distributed in the brain.
What is a common side effect of drugs that activate CB1 receptors?
Increased heart rate.
Fill in the blank: CB1 receptors are part of a larger family of __________ receptors.
Cannabinoid.
