GABA and Glycine Flashcards
Hyperpolarisation
A change in a cell’s membrane potential that takes it further away from 0mV.
Glutamate decarboxylase (GAD)
The enzyme that mediates the conversion of glutamate to GABA
GABA
A major inhibitory neurotransmitter in the CNS
Glycine
Another major inhibitory neurotransmitter in the CNS
Vesicular inhibitory amino acid transporter (VIAAT)
The transporter responsible for sequestering GABA and glycine into vesicles from the cytosol in the presynaptic bouton
GABA reuptake transporter (GAT)
The transporter responsible for sequestering GABA into the presynaptic bouton from the cytosol
GABA transaminase
The enzyme that breaks down GABA in the synaptic cleft
Panspermia
The theory that the universe contains the materials for the ‘building blocks’ of life
Glycine decarboxylase
The enzyme that breaks down Glycine in the synaptic cleft
Glycine reuptake transporter (GlyT)
The transporter responsible for sequestering glycine into the presynaptic bouton from the cytosol